A building blocks strategy is an effective approach for constructing the large molecular systems. Herein, we demonstrate that high‐resolution electro‐spray ionization mass spectrometry (HRESI‐MS) provides an effective chance to insight the assemble process of the building blocks and guides the construction of high‐nuclearity metal clusters on the basis of the reaction of Ti(OⁱPr)₄, Eu(acac)₃, and salicylic acid. The time‐dependent HRESI‐MS indicates that not only a Eu₃Ti building block can be formed, but that it can further assemble into a Eu₂₄Ti₈ compound. Temperature‐dependent HRESI‐MS reveals that increase of the reaction temperature favors the formation and crystallization of the stable Eu₂₄Ti₈ structure. Single‐crystal structural analysis demonstrates that the Eu₂₄Ti₈ has a wheel‐like structure with diameter of ca. 4.1 nm and is the highest nuclearity lanthanide‐titanium oxo cluster reported to date.

中文翻译：

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在高分辨率电喷雾电离质谱法的指导下组装类似车轮的Eu24Ti8团簇

构件策略是构建大分子系统的有效方法。本文中，我们证明了高分辨率电喷雾电离质谱（HRESI-MS）提供了一个有效的机会，以了解构建基块的组装过程，并在Ti反应的基础上指导高核金属簇的构建（O ⁱ Pr）₄，Eu（acac）₃和水杨酸。随时间变化的HRESI-MS表明，不仅可以形成Eu ₃ Ti构件，而且可以进一步组装成Eu ₂₄ Ti ₈化合物。与温度有关的HRESI-MS表明，反应温度的升高有利于稳定的Eu ₂₄ Ti ₈结构的形成和结晶。单晶结构分析表明，Eu ₂₄ Ti ₈具有轮状结构，直径约为。4.1 nm，是迄今为止报道的最高核度的镧系-钛氧基簇。