Comparison of metabolite networks from four German population-based studies,International Journal of Epidemiology

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Comparison of metabolite networks from four German population-based studies
International Journal of Epidemiology ( IF 7.7 ) Pub Date : 2018-07-02 , DOI: 10.1093/ije/dyy119
Khalid Iqbal ₁ , Stefan Dietrich _{2,

3} , Clemens Wittenbecher _{2,

3} , Jan Krumsiek _{3,

4} , Tilman Kühn ₅ , Maria Elena Lacruz ₆ , Alexander Kluttig _{3,

6} , Cornelia Prehn ₇ , Jerzy Adamski _{3,

7,

8} , Martin von Bergen ₉ , Rudolf Kaaks ₅ , Matthias B Schulze _{2,

3} , Heiner Boeing ₁ , Anna Floegel _{1,

10}

Affiliation

Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany
German Center for Diabetes Research (DZD), München-Neuherberg, Germany
Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany
Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University Halle-Wittenberg, Halle, Germany
Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising, Germany
Helmholtz Centre for Environmental Research—UFZ, Leipzig, Germany
Leibniz Institute for Prevention Research and Epidemiology—BIPS, Bremen, Germany

Metabolite networks are suggested to reflect biological pathways in health and disease. However, it is unknown whether such metabolite networks are reproducible across different populations. Therefore, the current study aimed to investigate similarity of metabolite networks in four German population-based studies.

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