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Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface
Theranostics ( IF 12.4 ) Pub Date : 2018-02-15 , DOI: 10.7150/thno.23674
Cuijun Deng , Huiying Zhu , Jiayi Li , Chun Feng , Qingqiang Yao , Liming Wang , Jiang Chang , Chengtie Wu

The cartilage lesion resulting from osteoarthritis (OA) always extends into subchondral bone. It is of great importance for simultaneous regeneration of two tissues of cartilage and subchondral bone. 3D-printed Sr5(PO4)2SiO4 (SPS) bioactive ceramic scaffolds may achieve the aim of regenerating both of cartilage and subchondral bone. We hypothesized that strontium (Sr) and silicon (Si) ions released from SPS scaffolds play a crucial role in osteochondral defect reconstruction.

中文翻译:

用于软骨和软骨下骨界面再生的生物活性支架

骨关节炎(OA)导致的软骨病变始终延伸到软骨下骨中。这对于同时使软骨和软骨下骨的两个组织再生非常重要。3D打印的Sr 5(PO 42 SiO 4(SPS)生物活性陶瓷支架可以实现再生软骨和软骨下骨的目的。我们假设从SPS支架释放的锶(Sr)和硅(Si)离子在骨软骨缺损重建中起关键作用。
更新日期:2018-07-01
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