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Synthesis of puleganic amides via a catalytically efficient two-step approach
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2018-06-30 , DOI: 10.1016/j.tetlet.2018.06.067
Ignacio Pérez , José Gustavo Ávila-Zárraga

Puleganic amides display interesting insect-repellent properties. A new synthetic route to this type of amide was developed involving an organocatalytic cyclization and metal-catalyzed hydrogenation in a one-pot protocol. An eco-friendly oxidative amination provided the puleganic amides with only one purification step and acceptable yields.



中文翻译:

通过催化有效的两步法合成多聚酰胺

Puleganic酰胺显示出有趣的驱蚊特性。已开发出一种新的合成这种酰胺的方法,该方法涉及一锅方案中的有机催化环化反应和金属催化的氢化反应。生态友好的氧化胺化仅需一个纯化步骤,即可为斑节胺提供可接受的收率。

更新日期:2018-06-30
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