This work evaluated the feasibility of pH-controlled fermentation by Lactobacillus plantarum CECT 748 combined with Savinase-hydrolysis (LPHS) for producing multifunctional lentil ingredients targeted for metabolic syndrome (MetS) relieving. LPHS process was compared with L. plantarum-fermentation (LP) and Savinase-hydrolysis (HS), applied separately. LPHS soluble fraction exhibited higher peptides, p-hydroxybenzoic acid, flavonols, antioxidant (400.74 mM TE/g), angiotensin I-converting enzyme (ACE) (95.43%) and α-glucosidase-inhibitory activities (40.55 and 25.03% for maltase and sacarase activities, respectively) than LP and HS. L. plantarum was responsible for the phenolic profile changes and sucrase inhibitory activity of LPHS while Savinase contributed to peptides release and ACE and maltase inhibitory and antioxidant activities. The most active LPHS fraction contained 3 peptides with potential biological activity and flavonoids and phenolic acids. LPHS simulated gastrointestinal digestion enhanced its peptides, phenolics, ACE-inhibitory and antioxidant activities. This study opens new opportunities regarding the production of lentil-multifunctional ingredients for MetS management.

这项工作评估了植物乳杆菌CECT 748与Savinase水解（LPHS）结合进行pH控制的发酵用于生产针对代谢综合征（MetS）缓解的多功能小扁豆成分的可行性。将LPHS工艺与植物乳杆菌发酵（LP）和Savinase水解（HS）（分别应用）进行了比较。LPHS可溶性级分显示出较高的肽，对羟基苯甲酸，黄酮醇，抗氧化剂（400.74 mM TE / g），血管紧张素I转化酶（ACE）（95.43％）和α-葡萄糖苷酶抑制活性（麦芽糖酶和淀粉酶分别为40.55和25.03％） Sacarase活性分别高于LP和HS。植物乳杆菌负责LPHS的酚类特征变化和蔗糖酶抑制活性，而Savinase有助于肽释放以及ACE和麦芽糖酶抑制和抗氧化活性。活性最强的LPHS馏分包含3种具有潜在生物活性的肽以及类黄酮和酚酸。LPHS模拟的胃肠道消化增强了其肽，酚类，ACE抑制和抗氧化活性。这项研究为用于MetS管理的扁豆多功能成分的生产提供了新的机会。