Deoxy-sugars often play a critical role in modulating the potency of many bioactive natural products. Accordingly, there has been sustained interest in methods for their synthesis over the past several decades. The focus of much of this work has been on developing new glycosylation reactions that permit the mild and selective construction of deoxyglycosides. This Review covers classical approaches to deoxyglycoside synthesis, as well as more recently developed chemistry that aims to control the selectivity of the reaction through rational design of the promoter. Where relevant, the application of this chemistry to natural product synthesis will also be described.

中文翻译：

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2-脱氧糖苷合成方法。

脱氧糖通常在调节许多生物活性天然产物的效力方面发挥着关键作用。因此，在过去的几十年里，人们对其合成方法一直感兴趣。这项工作的重点是开发新的糖基化反应，以温和且选择性地构建脱氧糖苷。本综述涵盖了脱氧糖苷合成的经典方法，以及最近开发的化学方法，旨在通过合理设计启动子来控制反应的选择性。在相关的情况下，还将描述该化学在天然产物合成中的应用。