The cover feature picture shows that PETase, a newly discovered enzyme from Ideonella sakaiensis, has high efficiency and specificity towards PET plastics compared to other similar enzymes (such as cutinase, esterase, or lipase). We have analyzed its crystal structure and improved its catalytic efficiency through site mutagenesis. The results suggest that this enzyme has valuable potential for further study and applications. More information can be found in the communication by Y. Luo, R. Bao, et al. on page 1471 in Issue 14, 2018 (DOI: 10.1002/cbic.201800097).

中文翻译：

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封面文章：酒井小枝蛾聚对苯二甲酸乙二酯水解酶PETase的蛋白质晶体学和位点直接诱变分析（ChemBioChem 14/2018）

封面特征图片显示，与其他类似的酶（如角质酶，酯酶或脂肪酶）相比，PET酶（一种来自大阪鸢尾的新发现的酶）对PET塑料具有较高的效率和特异性。我们已经分析了其晶体结构，并通过位点诱变提高了催化效率。结果表明该酶具有进一步研究和应用的宝贵潜力。可以在Y. Luo，R. Bao等人的来文中找到更多信息。就在第14期，2018页1471（：10.1002 / cbic.201800097 DOI）。