Luminescence from Lanthanide(III) Ions Bound to the Glycocalyx of Chinese Hamster Ovary Cells,Chemistry - A European Journal

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Luminescence from Lanthanide(III) Ions Bound to the Glycocalyx of Chinese Hamster Ovary Cells
Chemistry - A European Journal ( IF 4.3 ) Pub Date : 2018-07-18 , DOI: 10.1002/chem.201802799
Riikka Arppe‐Tabbara ₁ , Miguel R. Carro‐Temboury ₁ , Casper Hempel ₂ , Tom Vosch ₁ , Thomas Just Sørensen ₁

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Lanthanide(III) ions bind to the glycocalyx of Chinese Hamster Ovary (CHO) cells and give rise to a unique luminescent fingerprint. Following direct excitation of terbium(III) and europium(III) ions in the visible part of the spectrum, we are able to collect emission spectra pixel‐by‐pixel in images of CHO cells. Following data analysis that removes the background signal, the fine structure of the europium(III) luminescence indicate that the lanthanide(III) ions are bound to a single structure of the CHO cell glycocalyx. This was deduced from the fact that the structure‐sensitive emission spectrum of europium is unchanged throughout the investigated samples.

更新日期：2018-07-18

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