Two for one: A sol–gel process is applied for the co‐immobilization of whole cells of E. coli with C. violaceum ω‐transaminase activity and L. elongisporus with ketoreductase activity by entrapment by using silica microspheres as a supporting additive. The produced biocatalyst is used in the synthesis of enantiomerically pure amines and alcohols from racemic 4‐phenylbutan‐2‐amine and heptan‐2‐amine in a continuous‐flow mode.

中文翻译：

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具有ω-转氨酶和酮还原酶活性的共固定化全细胞用于连续流级联反应

两个用于一个：一个溶胶-凝胶过程被应用于全细胞的共固定化的大肠杆菌与C.堇色ω转氨酶活性和L. elongisporus通过使用二氧化硅微球作为支撑添加剂与酮还原酶活性由截留。所生产的生物催化剂用于以连续流模式从外消旋的4-苯基丁烷-2-胺和庚烷-2-胺合成对映体纯的胺和醇。