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Flexible‐Device Injector with a Microflap Array for Subcutaneously Implanting Flexible Medical Electronics
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2018-06-25 , DOI: 10.1002/adhm.201800419
Kwangsun Song 1, 2 , Juho Kim 1, 2 , Sungbum Cho 1 , Namyun Kim 1 , Dongwuk Jung 1, 2 , Hyuck Choo 3, 4 , Jongho Lee 1, 2
Affiliation  

Implantable electronics in soft and flexible forms can reduce undesired outcomes such as irritations and chronic damages to surrounding biological tissues due to the improved mechanical compatibility with soft tissues. However, the same mechanical flexibility also makes it difficult to insert such implants through the skin because of reduced stiffness. In this paper, a flexible‐device injector that enables the subcutaneous implantation of flexible medical electronics is reported. The injector consists of a customized blade at the tip and a microflap array which holds the flexible implant while the injector penetrates through soft tissues. The microflap array eliminates the need of additional materials such as adhesives that require an extended period to release a flexible medical electronic implant from an injector inside the skin. The mechanical properties of the injection system during the insertion process are experimentally characterized, and the injection of a flexible optical pulse sensor and electrocardiogram sensor is successfully demonstrated in vivo in live pig animal models to establish the practical feasibility of the concept.

中文翻译:

具有微瓣阵列的柔性设备注射器,用于皮下植入柔性医疗电子设备

由于改善了与软组织的机械相容性,软和柔性形式的可植入电子设备可以减少不希望的结果,例如刺激和对周围生物组织的慢性损害。然而,由于刚度降低,相同的机械柔韧性也使得难以将这种植入物穿过皮肤插入。在本文中,报道了一种柔性设备注射器,该注射器能够皮下植入柔性医疗电子设备。注射器由尖端的定制刀片和微瓣阵列组成,该微瓣阵列在注射器穿透软组织时将柔性植入物固定住。微瓣阵列消除了对诸如粘合剂之类的额外材料的需求,这些材料需要更长的时间才能从皮肤内的注射器释放柔性医疗电子植入物。
更新日期:2018-06-25
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