Identification of Comprehensive Metabotypes Associated with Cardiometabolic Diseases in the Population‐Based KORA Study,Molecular Nutrition & Food Research

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Identification of Comprehensive Metabotypes Associated with Cardiometabolic Diseases in the Population‐Based KORA Study
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-07-31 , DOI: 10.1002/mnfr.201800117
Anna Riedl _{1,

2,

3,

4} , Nina Wawro _{1,

2,

3,

4} , Christian Gieger _{2,

3,

5} , Christa Meisinger _{1,

2,

4} , Annette Peters _{2,

3} , Michael Roden _{3,

6,

7} , Florian Kronenberg ₈ , Christian Herder _{3,

7} , Wolfgang Rathmann _{3,

9} , Henry Völzke _{3,

10,

11} , Martin Reincke ₁₂ , Wolfgang Koenig _{10,

13,

14} , Henri Wallaschofski ₁₅ , Hans Hauner _{16,

17,

18,

19} , Hannelore Daniel ₁₉ , Jakob Linseisen _{1,

2,

4,

17}

Affiliation

Independent Research Group Clinical Epidemiology; Helmholtz Zentrum München; German Research Center for Environmental Health; Ingolstädter Landstr. 1 85764 Neuherberg Germany
Institute of Epidemiology II; Helmholtz Zentrum München; German Research Center for Environmental Health; Ingolstädter Landstr. 1 85764 Neuherberg Germany
German Center for Diabetes Research; Ingolstädter Landstr. 1 85764 Neuherberg Germany
Chair of Epidemiology; Ludwig-Maximilians-Universität München; at UNIKA-T (Universitäres Zentrum für Gesundheitswissenschaften am Klinikum Augsburg); Neusässer Str. 47 86156 Augsburg Germany
Research Unit of Molecular Epidemiology; Helmholtz Zentrum München; German Research Center for Environmental Health (GmbH); Ingolstädter Landstr. 1 85764 Neuherberg Germany
Division of Endocrinology and Diabetology; Medical Faculty; Heinrich Heine University Düsseldorf; Auf'm Hennekamp 65 40225 Düsseldorf Germany
Institute for Clinical Diabetology; German Diabetes Center; Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf; Auf'm Hennekamp 65 40225 Düsseldorf Germany
Division of Genetic Epidemiology; Department of Medical Genetics; Molecular and Clinical Pharmacology; Medical University of Innsbruck; Schöpfstr. 41 6020 Innsbruck Austria
Institute for Biometrics and Epidemiology; German Diabetes Center; Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf; Auf'm Hennekamp 65 40225 Düsseldorf Germany
DZHK - German Centre for Cardiovascular Research; Partner Site Munich Heart Alliance; Pettenkoferstr. 8a & 9 80336 Munich Germany
Institute for Community Medicine; University Medicine Greifswald; Walther-Rathenau-Str. 48 17475 Greifswald Germany
Medizinische Klinik und Poliklinik IV; Klinikum der Universität München; Ludwig-Maximilians-Universität München; Ziemssenstr. 1 81377 Munich Germany
Deutsches Herzzentrum München; Technische Universität München; Lazarettstr. 36 80636 Munich Germany
Department of Internal Medicine II-Cardiology; University of Ulm Medical Center; Albert-Einstein-Allee 23 89081 Ulm Germany
Institute of Clinical Chemistry and Laboratory Medicine; University Medicine Greifswald; Ferdinand-Sauerbruch-Str. 17489 Greifswald Germany
Else Kröner-Fresenius Centre for Nutritional Medicine; Technical University of Munich; Gregor-Mendel-Str. 2 85354 Freising-Weihenstephan Germany
ZIEL - Institute for Food and Health; Technical University of Munich; Weihenstephaner Berg 1 85354 Freising Germany
Institute of Nutritional Medicine; Klinikum rechts der Isar; Technical University of Munich; Uptown München Campus D, Georg-Brauchle-Ring 60/62 80992 Munich Germany
Technical University of Munich; Gregor-Mendel-Str. 2 85354 Freising-Weihenstephan Germany

“Metabotyping” describes the grouping of metabolically similar individuals. We aimed to identify valid metabotypes in a large cohort for targeted dietary intervention, for example, for disease prevention.

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