Objective

The aim of this study was to assess the degradation behavior by measuring the H₂ release of a biodegradable composite consisting of a polylactic acid matrix reinforced with 30% wt. spherical magnesium microparticles (PLA/Mg) as potential bone augmentation material in combination with dental implants of either titanium or polyetheretherketone (PEEK) in order to evaluate the potential influence of the titanium dental implants on the corrosion behavior of the Mg particles within the PLA matrix.

Methods

Three PEEK dental implants and three titanium dental implants were put into a central perforation of six PLA/Mg-discs. These samples were incubated at 37 °C for 30 days in McCoy’s 5A modified medium and the H₂ release was evaluated.

Results

Between day 7 and day 16 the average H₂ release per cm² of the surface of the PLA/Mg-samples in combination with the titanium implants was significantly higher than that of the sample group combined with the implants of PEEK (3.1 ± 0.4 ml vs. 2.8 ± 0.4 ml). This significant difference disappeared afterwards, whereas the H₂ release was highest at day 30 and amounted 3.5 ± 0.7 ml/cm² for the group with the titanium implants and 3.2 ± 0.8 ml/cm² for the group with the PEEK implants.

Significance

Regarding the similar values of the degradation depending H₂ release of the two implant material groups, the co-implantation of a PLA/Mg composite is not only possible with new metal-free implant materials such as PEEK, but also with conventional implants of titanium.

中文翻译：

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在钛和PEEK牙植入物的存在下，可生物降解的聚乳酸/镁复合材料作为潜在的骨增强材料的体外降解

客观的

这项研究的目的是通过测量由30％wt增强的聚乳酸基质组成的可生物降解复合材料的H ₂释放来评估其降解行为。球形镁微粒（PLA / Mg）作为潜在的骨增强材料，与钛或聚醚醚酮（PEEK）的牙科植入物结合使用，以评估钛牙科植入物对PLA基质中Mg颗粒腐蚀行为的潜在影响。

方法

将三个PEEK牙科植入物和三个钛牙科植入物放入六个PLA / Mg椎间盘的中央穿孔中。将这些样品在McCoy的5A修饰培养基中于37°C孵育30天，并评估H ₂释放。

结果

在第7天和第16天之间，结合钛植入物的PLA / Mg样品的表面每cm ²的平均H ₂释放量显着高于结合PEEK植入物的样品组的平均H ₂释放量（3.1±0.4 ml vs. 2.8±0.4 ml）。此显着差异随后消失，而H ₂释放在第30天最高，对于钛植入物组为3.5±0.7 ml / cm ²，而对于PEEK植入物组为3.2±0.8 ml / cm ²。

意义

关于取决于两个植入物材料组释放H ₂的降解的相似值，不仅可以与新型无金属植入物材料（例如PEEK）共同植入PLA / Mg复合材料，而且还可以与常规的钛植入物一起植入。