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Design of tailored biodegradable implants: The effect of voltage on electrodeposited calcium phosphate coatings on pure magnesium
Journal of the American Ceramic Society ( IF 3.9 ) Pub Date : 2018-07-02 , DOI: 10.1111/jace.15888
Miroslava Horynová 1 , Michaela Remešová 1 , Lenka Klakurková 1 , Karel Dvořák 2 , Ivana Ročňáková 1 , Shaokun Yan 3 , Ladislav Čelko 1 , Guang-Ling Song 3
Affiliation  

Magnesium, as a biodegradable metal, offers great potential for use as a temporary implant material, which dissolves in the course of bone tissue healing. It can sufficiently support the bone and promote the bone healing process. However, the corrosion resistance of magnesium implants must be enhanced before its application in clinical practice. A promising approach of enhancing the corrosion resistance is deposition of bioactive coating, which can reduce the corrosion rate of the implants and promote bone healing. Therefore, a well‐designed substrate‐coating system allowing a good control of the degradation behavior is highly desirable for tailored implants for specific groups of patients with particular needs. In this contribution, the influence of coating formation conditions on the characteristics of potentiostatically electrodeposited CaP coatings on magnesium substrate was evaluated. Results showed that potential variation led to formation of coatings with the same chemical composition, but very different morphologies. Parameters that mostly influence the coating performance, such as the thickness, uniformity, deposits size, and orientation, varied from produced coating to coating. These characteristics of CaP coatings on magnesium were controlled by coating formation potential, and it was demonstrated that the electrodeposition could be a promising coating technique for production of tailored magnesium‐CaP implants.

中文翻译:

量身定制的可生物降解植入物的设计:电压对纯镁上电沉积磷酸钙涂层的影响

镁作为一种可生物降解的金属,具有巨大的潜力,可以用作暂时的植入材料,并在骨骼组织愈合过程中溶解。它可以充分支撑骨骼并促进骨骼愈合过程。但是,在将镁植入物用于临床之前,必须增强其耐腐蚀性。增强抗腐蚀性的一种有前途的方法是生物活性涂层的沉积,它可以降低植入物的腐蚀速率并促进骨骼愈合。因此,对于具有特殊需要的特定患者群体的定制植入物,非常需要设计良好的底物涂覆系统,以很好地控制降解行为。在这笔捐款中,评估了涂层形成条件对镁基体上恒电位电沉积CaP涂层特性的影响。结果表明,电位变化导致形成具有相同化学组成但形态非常不同的涂层。影响涂层性能的参数(例如厚度,均匀性,沉积物尺寸和方向)在生产的涂层之间各不相同。镁上的CaP涂层的这些特性受涂层形成电势的控制,并且证明了电沉积可能是生产定制的镁-CaP植入物的有前途的涂层技术。但形态却大不相同。影响涂层性能的参数(例如厚度,均匀性,沉积物尺寸和方向)在生产的涂层之间各不相同。镁上的CaP涂层的这些特性受涂层形成电势的控制,并且证明了电沉积可能是生产定制的镁-CaP植入物的有前途的涂层技术。但形态却大不相同。影响涂层性能的参数(例如厚度,均匀性,沉积物尺寸和方向)在生产的涂层之间各不相同。镁上的CaP涂层的这些特性受涂层形成电势的控制,并且证明了电沉积可能是生产定制的镁-CaP植入物的有前途的涂层技术。
更新日期:2018-07-02
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