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Synthesis of acyloxyl pyrazolines by copper-mediated aminoacyloxylation of unsaturated ketohydrazones†
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2018-06-21 00:00:00 , DOI: 10.1039/c8ob01114a
Manman Chen 1, 2, 3, 4 , Lin Qi 1, 2, 3, 4 , Jia-Min Chen 1, 2, 3, 4 , Pei-Xing Ren 1, 2, 3, 4 , Jie Du 1, 2, 3, 4 , Li-Jing Wang 1, 2, 3, 4, 5 , Wei Li 1, 2, 3, 4, 5
Affiliation  

An efficient and step-economical copper-mediated intra-/intermolecular aminoacyloxylation of β,γ-unsaturated hydrazones has been developed. Copper carboxylates serve as both reaction promoters and carboxylate sources in these easily conducted reactions. This method provides straightforward access to diversely useful acyloxyl pyrazolines, which are hard to access traditionally, in good to excellent yields.

中文翻译:

铜介导的不饱和酮hydr的氨基酰氧基合成酰氧基吡唑啉

已经开发了一种有效且分步经济的铜介导的β,γ-不饱和的分子内/分子间氨酰氧基化反应。在这些容易进行的反应中,羧酸铜既充当反应促进剂又充当羧酸来源。该方法可以直接获得各种有用的酰氧基吡唑啉,而传统上难以获得的酰氧基吡唑啉具有良好或优异的收率。
更新日期:2018-06-21
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