The determination of biological thiols is considered to be of great interest because of the participation of these molecules in physiological disorders as indicators of their existence and progress, such as Alzheimer’s disease, cancer, and cystic fibrosis, among others. Optical techniques for the quantification of these analytes are superior to other techniques in terms of selectivity, sensitivity, and cost. We describe here a simple protocol to determine biological thiols by means of a colorimetric analysis based on a magenta color interaction with 5,5′-dithiobis(2-nitrobenzoic acid). This methodology leverages the technology developed in smartphones, and it can be transferred to a simple analytical procedure through the use of absorbent strips and a cell phone. Excellent characteristics were observed, and this method opens up alternative avenues for the detection of biological thiols in a very simple and portable manner.

中文翻译：

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通过未报告的品红色相互作用选择性筛选生物硫醇，并使用智能手机进行评估

由于这些分子参与生理疾病作为其存在和进展的指标，例如阿尔茨海默氏病，癌症和囊性纤维化等，因此认为生物硫醇的测定引起了人们的极大兴趣。在选择性，灵敏度和成本方面，用于定量分析物的光学技术优于其他技术。我们在这里描述了一种简单的协议，该方法通过比色分析基于与5，5'-二硫代双（2-硝基苯甲酸）的品红色相互作用来确定生物硫醇。这种方法论利用了智能手机中开发的技术，并且可以通过使用吸收条和手机将其转换为简单的分析程序。观察到优异的特性，