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Implication of the Significance of Dietary Compatibility: Based on the Antioxidant and Anti-Inflammatory Interactions with Different Ratios of Hydrophilic and Lipophilic Antioxidants among Four Daily Agricultural Crops
Journal of Agricultural and Food Chemistry ( IF 6.1 ) Pub Date : 2018-06-19 00:00:00 , DOI: 10.1021/acs.jafc.8b01690
Yao Pan 1 , Hongyan Li 1 , Shilian Zheng 1 , Bing Zhang 1 , Ze-yuan Deng 1, 2
Affiliation  

The hydrophilic extracts of eggplant peel (HEEP) and purple sweet potato (HEPP) and lipophilic extracts of tomato (LET) and carrot (LEC) were mixed in different ratios to assess the significance of the compatibility of aliments, based on their antioxidant and anti-inflammatory interactions in H9c2 cells. The results indicated that groups of some combinational extracts (HEPP-HEEP F1/10, LEC-HEEP F3/10, LEC-HEPP F3/10) showed stronger synergistic antioxidant and anti-inflammatory effects than individual groups. For example, the glutathione peroxidase (GPx) activity of the LEC-HEEP (F3/10) group (86.71 ± 1.88) was higher than that in the HEEP (79.97 ± 1.68) and LEC (77.31 ± 1.85) groups. The level of reactive oxygen species (ROS) was 30.37 ± 0.25 in the LEC-HEEP (F3/10) group while the levels were 34.34 ± 0.36 and 46.23 ± 0.51 in the HEEP and LEC groups, respectively. And the level of malondialdehyde (MDA) was 1.82 ± 0.24 in the LEC-HEEP (F3/10) group while the levels were 2.48 ± 0.13 and 3.01 ± 0.24 in the HEEP and LEC groups, respectively. The expressions of inflammatory mediators (IL-1β, IL-6, IL-8) and cell adhesion molecules (VCAM-1, ICAM-1) showed similar tendencies. However, some groups (LET-LEC F5/10, LET-LEC F9/10, LET-HEPP F7/10) showed antagonistic effects based on these indicators. The principal component analysis showed that samples could be defined by two principal components: PC1, the main phenolic acids and flavonoids; PC2, carotenoids. Moreover, phenolics and anthoyanins were in the majority in synergistic groups, and carotenoids were in the majority in antagonistic groups. These results indicated that there exist synergistic or antagonistic interactions of aliments on antioxidation and anti-inflammation, which implied the significance of food compatibility.

中文翻译:

饮食相容性意义的涵义:基于每日四种农作物中不同比例的亲水性和亲脂性抗氧化剂的抗氧化剂和抗炎相互作用

混合不同比例的茄子皮(HEEP)和紫色甘薯(HEPP)的亲水性提取物,番茄(LET)和胡萝卜(LEC)的亲脂性提取物,以评估它们的抗氧化剂和抗氧化剂的相容性的重要性。 -H9c2细胞中的炎症相互作用。结果表明,某些组合提取物组(HEPP-HEEP F1 / 10,LEC-HEEP F3 / 10,LEC-HEPP F3 / 10)显示出比单个组更强的协同抗氧化和抗炎作用。例如,LEC-HEEP(F3 / 10)组(86.71±1.88)的谷胱甘肽过氧化物酶(GPx)活性高于HEEP(79.97±1.68)和LEC(77.31±1.85)组的谷胱甘肽过氧化物酶(GPx)活性。LEC-HEEP(F3 / 10)组的活性氧(ROS)水平为30.37±0.25,而水平分别为34.34±0.36和46.23±0。HEEP和LEC组分别为51。在LEC-HEEP(F3 / 10)组中,丙二醛(MDA)的水平为1.82±0.24,而在HEEP和LEC组中,丙二醛的水平分别为2.48±0.13和3.01±0.24。炎性介质(IL-1β,IL-6,IL-8)和细胞粘附分子(VCAM-1,ICAM-1)的表达趋势相似。但是,基于这些指标,一些组(LET-LEC F5 / 10,LET-LEC F9 / 10,LET-HEPP F7 / 10)表现出拮抗作用。主成分分析表明,样品可以由两个主成分定义:PC1,主要酚酸和类黄酮; PC1,主要酚酸和类黄酮。PC2,类胡萝卜素。此外,在协同组中,酚类和花色素苷最多,而拮抗组中类胡萝卜素最多。
更新日期:2018-06-19
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