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Low-power, low-cost urinalysis system with integrated dipstick evaluation and microscopic analysis
Lab on a Chip ( IF 6.1 ) Pub Date : 2018-06-19 00:00:00 , DOI: 10.1039/c8lc00501j
Gennifer T. Smith 1, 2, 3, 4 , Linkai Li 1, 2, 3, 4 , Yue Zhu 1, 2, 3, 4 , Audrey K. Bowden 1, 2, 3, 4, 5
Affiliation  

We introduce a coupled dipstick and microscopy device for analyzing urine samples. The device is capable of accurately assessing urine dipstick results while simultaneously imaging the microscopic contents within the sample. We introduce a long working distance, cellphone-based microscope in combination with an oblique illumination scheme to accurately visualize and quantify particles within the urine sample. To facilitate accurate quantification, we couple the imaging set-up with a power-free filtration system. The proposed device is reusable, low-cost, and requires very little power. We show that results obtained with the proposed device and custom-built app are consistent with those obtained with the standard clinical protocol, suggesting the potential clinical utility of the device.

中文翻译:

低功耗,低成本的尿液分析系统,具有集成的量油尺评估和微观分析功能

我们介绍了一种用于分析尿液样本的量油尺和显微镜相结合的装置。该设备能够准确评估尿液量尺结果,同时对样品中的微观内容物进行成像。我们引入了基于手机的长距离工作显微镜,并结合了倾斜照明方案,以准确地可视化和量化尿液样本中的颗粒。为了促进精确定量,我们将成像设置与无动力过滤系统结合在一起。所提出的设备是可重复使用的,低成本的,并且需要很少的功率。我们显示,使用建议的设备和定制的应用程序获得的结果与通过标准临床协议获得的结果一致,表明该设备具有潜在的临床实用性。
更新日期:2018-06-19
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