In this study, SBA-15/Fe₃O₄ nanocomposites were prepared by conjugating Fe₃O₄ nanoparticles to mesoporous silica SBA-15 particles as magnetically recoverable adsorbents. The physicochemical and magnetic properties of bare and as-prepared samples were characterized using the X-ray diffractometer, transmission electron microscope, Fourier transform infrared spectroscope, porosimeter, and vibrating sample magnetometer. The performance of SBA-15, Fe₃O₄, and SBA-15/Fe₃O₄ nanocomposites for adsorption removal of uremic toxin urea in simulated serum was compared at 25 and 37°C. Except for Fe₃O₄, both SBA-15 and SBA-15/Fe₃O₄ showed a high and equivalent adsorption ability for urea. Although the surface area of SBA-15/Fe₃O₄ nanocomposites decreased from 1167 m²/g (bare SBA-15) to 311 m²/g, the pore volume of SBA-15/Fe₃O₄ was not greatly decreased because most of Fe₃O₄ nanoparticles were coated onto the surface of SBA-15 particles. The adsorption mechanism of urea on SBA-15/Fe₃O₄ was proposed. Finally, the cytotoxicity of SBA-15/Fe₃O₄ nanocomposites before and after urea adsorption for fibroblast L929 cells was studied.

在这项研究中，SBA-15 / Fe ₃ O ₄纳米复合材料是通过将Fe ₃ O ₄纳米颗粒与作为磁性可回收吸附剂的中孔二氧化硅SBA-15颗粒共轭而制备的。使用X射线衍射仪，透射电子显微镜，傅立叶变换红外光谱仪，孔隙率计和振动样品磁力计对裸露和制备好的样品的物理化学和磁性进行了表征。在25和37处比较了SBA-15，Fe ₃ O ₄和SBA-15 / Fe ₃ O ₄纳米复合材料吸附去除模拟血清中尿毒症尿素的性能。℃。除了Fe ₃ O _4以外，SBA-15和SBA-15 / Fe ₃ O ₄均显示出对尿素的高等价吸附能力。尽管SBA-15 / Fe ₃ O ₄纳米复合材料的表面积从1167 m ² / g（裸露SBA-15）减少到311 m ² / g，但SBA-15 / Fe ₃ O ₄的孔体积并未大大减小因为大多数Fe ₃ O ₄纳米颗粒都被涂覆在SBA-15颗粒的表面上。提出了尿素在SBA-15 / Fe ₃ O ₄上的吸附机理。最后，SBA-15 / Fe ₃的细胞毒性研究了尿素吸附成纤维细胞L929细胞前后的O ₄纳米复合材料。