Abstractβ-Cyclodextrin (β-CD) possess a hydrophobic inner cavity and a hydrophilic exterior surface. They exhibit excellent inclusion properties with the guest molecules that match cavity size, and β-CD-based materials drew widespread attention in electrochemical sensors. The hydroxy groups at the edge of the cavity can form hydrogen bonds and undergo electrostatic and dipole-dipole interactions with other molecules. This review (with 109 refs.) reveals β-CD-based detection mechanisms from the viewpoint of the size/shape-fit concept, and summarizes the current state of multiple electrochemical sensors based on the use of β-CD and functionalized β-CD such as carboxymethyl-β-CD, mono-(6-ethanediamine-6-deoxy)-β-CD, hydroxypropyl-β-CD, thio-β-cyclodextrin, and others. Graphical abstractSchematic diagram of cyclodextrin inclusion complex formation in aqueous solution, represents water molecules, represents guest molecule.

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β-环糊精功能复合材料在电化学传感器中的应用进展

摘要β-环糊精（β-CD）具有疏水内腔和亲水外表面。它们与匹配腔尺寸的客体分子表现出优异的包含特性，基于 β-CD 的材料在电化学传感器中引起了广泛关注。空腔边缘的羟基可以形成氢键，并与其他分子发生静电和偶极-偶极相互作用。这篇综述（有 109 篇参考文献）从尺寸/形状拟合概念的角度揭示了基于 β-CD 的检测机制，并总结了基于使用 β-CD 和功能化 β-CD 的多种电化学传感器的当前状态如羧甲基-β-CD、单-(6-乙二胺-6-脱氧)-β-CD、羟丙基-β-CD、硫代-β-环糊精等。