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Natural Products for the Prevention and Management of Helicobacter pylori Infection
Comprehensive Reviews in Food Science and Food Safety ( IF 14.8 ) Pub Date : 2018-06-15 , DOI: 10.1111/1541-4337.12355
Qing Liu 1 , Xiao Meng 1 , Ya Li 1 , Cai-Ning Zhao 1 , Guo-Yi Tang 1 , Sha Li 2 , Ren-You Gan 3 , Hua-Bin Li 1, 4
Affiliation  

Helicobacter pylori is the main pathogen that induces chronic gastritis, peptic ulcers, atrophic gastritis, and other gastric disorders, and it is classified as a group I carcinogen. To eradicate H. pylori infection, triple therapy consisting of two antibiotics and a proton pump inhibitor is the most widely recommended first‐line therapeutic strategy. Antimicrobial resistance to antibiotics contained in triple therapy could lead to therapeutic regimen failures. Recent studies showed that many natural products, including fruits, vegetables, spices, and medicinal plants, possess inhibitory effects on H. pylori, indicating their potential to be alternatives to prevent and manage H. pylori infection. This review summarizes the effects of natural products on H. pylori infection and highlights the mechanisms of action.

中文翻译:

预防和管理幽门螺杆菌感染的天然产品

幽门螺杆菌是引起慢性胃炎,消化性溃疡,萎缩性胃炎和其他胃部疾病的主要病原体,被归为第一类致癌物。为根除幽门螺杆菌感染,最广泛推荐的一线治疗策略是由两种抗生素和质子泵抑制剂组成的三联疗法。三联疗法中包含的对抗生素的抗药性可能导致治疗方案失败。最近的研究表明,许多天然产品,包括水果,蔬菜,香料和药用植物,对幽门螺杆菌都有抑制作用,表明它们有可能成为预防和管理幽门螺杆菌的替代品感染。这篇综述总结了天然产物对幽门螺杆菌感染的影响,并强调了其作用机理。
更新日期:2018-06-15
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