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Chlorogenic Acid from Hawthorn Berry (Crataegus pinnatifida Fruit) Prevents Stress Hormone‐Induced Depressive Behavior, through Monoamine Oxidase B‐Reactive Oxygen Species Signaling in Hippocampal Astrocytes of Mice
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-07-11 , DOI: 10.1002/mnfr.201800029
Dong Wook Lim 1 , Taewon Han 1, 2 , Jonghoon Jung 1 , Yuri Song 1 , Min Young Um 1, 3 , Minseok Yoon 1 , Yun Tai Kim 1 , Seungmok Cho 1 , In-Ho Kim 1 , Daeseok Han 1 , Changho Lee 1 , Jaekwang Lee 1
Affiliation  

Oxidative stress has been implicated in mental disorders, including depression. Chlorogenic acid (CGA), one of the abundant phenolic compounds in herbs and fruits, has the properties of a natural antioxidant and free‐radical scavenger. Therfore, we investigated the antidepressant‐like effects and active mechanisms of CGA from the extract of Crataegus pinnatifida (CP) fruit.

中文翻译:

来自山楂浆果(Crataegus pinnatifida 果实)的绿原酸通过小鼠海马星形胶质细胞中的单胺氧化酶 B 反应性氧物种信号传导预防应激激素诱导的抑郁行为

氧化应激与精神障碍有关,包括抑郁症。绿原酸 (CGA) 是草药和水果中丰富的酚类化合物之一,具有天然抗氧化剂和自由基清除剂的特性。因此,我们研究了山楂(CP) 果实提取物中 CGA 的抗抑郁样作用和活性机制。
更新日期:2018-07-11
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