Carbohydrate chemistry has benefited a lot from the intrinsic reactivity of sulfoxide since it was introduced in glycosylation reactions by Kahne in 1989. Since then, extensive studies have been explored by employing sulfoxide as glycosyl donors and activation reagents in construction of glycosidic bonds. As glycosyl donors, the sulfinyl groups could locate either directly or remotely at anomeric position. This chapter focuses on the establishment and development of sulfoxides as glycosyl donors in glycosylation reactions, with an emphasis on their applications and postulated mechanisms.

中文翻译：

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糖基化反应中的糖基亚砜

自1989年Kahne在糖基化反应中引入亚砜以来，碳水化合物化学就从亚砜的内在反应性中受益匪浅。此后，通过使用亚砜作为糖基供体和活化剂来构建糖苷键，人们进行了广泛的研究。作为糖基供体，亚磺酰基可直接或位于异头位置。本章重点介绍亚砜在糖基化反应中作为糖基供体的建立和发展，重点是它们的应用和假定的机制。