Polysaccharides extracted from plants are very promising molecules in the field of pharmacotherapy. Knowing this, the aim of this study was to extract, characterize and evaluate the action of the polysaccharide of Morinda citrifolia Linn (Noni-PLS) in biological models of inflammatory processes. The characterization tests shown that sample refers to a heteropolysaccharide composed mainly of homogalacturonan and rhamnogalacturonan. This polysaccharide at dose of 10 mg/kg, when tested in our models of inflammation, showed significant activity in reducing carrageenan-induced paw oedema as well as all mediators edemas. This polysaccharide was able to inhibit the migration of leukocytes to the site of inflammation, and still reduced inflammatory nociception tests. This results, allows us to conclude that the polysaccharide extracted from Morinda citrifolia linn has anti-inflammatory potential since it reversed inflammatory parameters such as edema, leukocyte migration and nociception.

从植物中提取的多糖是药物治疗领域中非常有前途的分子。知道这一点，本研究的目的是提取，表征和评估巴戟天多糖的作用。（Noni-PLS）在炎症过程的生物学模型中。表征测试表明，样品是指主要由高半乳糖醛酸聚糖和鼠李糖半乳糖醛酸聚糖组成的杂多糖。当在我们的炎症模型中进行测试时，这种10 mg / kg的多糖在减少角叉菜胶引起的爪水肿以及所有介质水肿方面显示出显着的活性。该多糖能够抑制白细胞向炎症部位的迁移，并且仍然减少了炎症伤害感受测试。该结果使我们得出结论，从巴戟天提取的多糖具有抗炎潜力，因为它逆转了诸如水肿，白细胞迁移和伤害感受的炎症参数。