Abstract Some chronic illnesses do not show any symptoms at an early stage, which causes a difficult to treating the situation. Especially cardiovascular diseases, liver functions and cancer could be prevented at early stages of diseases by advanced biomedical imaging techniques. In this study, indocyanine green (ICG), which must be stabilized in aqueous media for the development of its use in biomedical applications, was stabilized by encapsulating into the biodegradable polymer of poly(lactic acid) (PLA) using a coaxial electrospinning (CES) method to produce ICG near infrared (NIR) fluorophore nanoprobe with the one-step process.

中文翻译：

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将吲哚菁绿封装在聚乳酸纳米纤维中，用作生物医学诊断中的纳米探针

摘要 一些慢性病早期没有任何症状，导致治疗困难。特别是心血管疾病、肝功能和癌症可以通过先进的生物医学成像技术在疾病的早期阶段进行预防。在这项研究中，必须在水性介质中稳定以开发其在生物医学应用中的应用的吲哚菁绿 (ICG)，通过使用同轴静电纺丝 (CES) 封装到聚乳酸 (PLA) 的可生物降解聚合物中来稳定) 通过一步法生产 ICG 近红外 (NIR) 荧光团纳米探针的方法。