Comprehensive two-dimensional gas chromatography (GC × GC) has become accepted as one of the most powerful separation techniques in several application areas. In forensic investigations, however, it has not yet been entirely established due to limitations regarding standardized methodology, data interpretation and consistency of results. Nevertheless, GC × GC allows for target analysis, compound class analysis and chemical fingerprinting of samples and is therefore increasingly applied in forensic analytics. In this review, recent and significant advances in GC × GC for application to forensic studies including human scent, arson investigations, security-relevant substances and environmental forensics are discussed. The discussion includes a brief overview of the latest trends and evolutions with regard to the various forensic applications and data evaluation as well as limitations. This leads to the conclusion that the full potential of the comprehensive data sets can only be achieved by implementing standardized analysis and data processing methods.

全面的二维气相色谱仪（GC×GC）已被接受为几个应用领域中最强大的分离技术之一。然而，在法医调查中，由于标准化方法，数据解释和结果一致性方面的局限性，因此尚未完全确定。尽管如此，GC×GC仍可进行目标分析，化合物类别分析和样品的化学指纹分析，因此越来越多地应用于法医分析中。在这篇综述中，讨论了GC×GC在法医学研究中的最新和重要进展，包括人体气味，纵火调查，与安全相关的物质和环境法医学。讨论内容包括对各种取证应用和数据评估以及局限性的最新趋势和发展的简要概述。由此得出的结论是，只有通过实施标准化的分析和数据处理方法，才能充分发挥综合数据集的全部潜力。