We have fabricated a flexible membrane, consisting of SiO₂ nanofibres armoured with upconversion nanoparticles, exhibiting intense photoluminescence. These assemblies were subsequently grafted with molecular beacons to produce a biosensor suitable for the detection of specific microRNA and with applications in early cancer detection and point-of-care diagnosis.

中文翻译：

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具有超强光致发光特性的上转换纳米晶体“铠装”二氧化硅纤维，可用于miRNA检测†

我们制造了一种柔性膜，该膜由装满上转换纳米颗粒的SiO ₂纳米纤维组成，具有强烈的光致发光特性。随后将这些组件与分子信标嫁接在一起，以生产适用于检测特定microRNA的生物传感器，并将其应用于早期癌症检测和即时诊断。