Arsenic (As) exhibits diverse (bio)chemical reactivity and biological activity depending upon its oxidation state. However, this distinctive reactivity has been largely overlooked across many fields owing to concerns regarding the toxicity of arsenic. Recently, a clinical renaissance in the use of arsenicals, including organic arsenicals that are known to be less toxic than inorganic arsenicals, alludes to the possibility of broader acceptance and application in the field of polymer and biomaterials science. Here, current examples of polymeric/macromolecular arsenicals are reported to stimulate interest and highlight their potential as a novel platform for functional, responsive, and bioactive materials.

中文翻译：

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有机砷作为聚合物和生物材料科学中的功能母题

砷（As）根据其氧化态表现出不同的（生物）化学反应性和生物活性。然而，由于担心砷的毒性，这种独特的反应性已在许多领域被广泛忽视。近来，使用包括有机砷的砷在内的砷的临床复兴表明其毒性要比无机砷低，这暗示了在聚合物和生物材料科学领域更广泛地被接受和应用的可能性。在这里，据报道聚合物/大分子砷的当前例子激发了人们的兴趣，并突出了它们作为功能性，响应性和生物活性材料的新型平台的潜力。