当前位置: X-MOL 学术Nat. Med. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Modeling cytokine release syndrome
Nature Medicine ( IF 82.9 ) Pub Date : 2018-05-28 , DOI: 10.1038/s41591-018-0068-9
Cliona Rooney , Tim Sauer

Modeling cytokine release syndrome

Modeling cytokine release syndrome, Published online: 28 May 2018; doi:10.1038/s41591-018-0068-9

Complete leukemic responses to chimeric antigen receptor–modified T cells are invariably accompanied by severe toxicity. Recently developed animal models allow mechanistic dissection and prevention of toxicity without loss of therapeutic benefit.


中文翻译:

模拟细胞因子释放综合征

模拟细胞因子释放综合征

模拟细胞因子释放综合征,在线发布:2018年5月28日; doi:10.1038 / s41591-018-0068-9

对嵌合抗原受体修饰的T细胞的完全白血病反应总是伴随着严重的毒性反应。最近开发的动物模型可以进行机械解剖并预防毒性,而不会失去治疗效果。
更新日期:2018-05-29
down
wechat
bug