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Cohort profile: The Childhood Asthma Prevention Study (CAPS)
International Journal of Epidemiology ( IF 7.7 ) Pub Date : 2018-05-25 , DOI: 10.1093/ije/dyy078
Frances L Garden 1, 2, 3 , Brett G Toelle 3, 4 , Seema Mihrshahi 5 , Karen L Webb 6 , Catarina Almqvist 7, 8 , Euan R Tovey 3 , Bronwyn K Brew 7 , Julian G Ayer 5, 9 , Michael R Skilton 5, 10 , Graham Jones 11 , Manuel A R Ferreira 12 , Christine T Cowie 1, 2, 3 , Christina Weber-Chrysochoou 13 , Warwick J Britton 5, 14 , David S Celermajer 5, 15 , Stephen R Leeder 16 , Jennifer K Peat 3 , Guy B Marks 1, 2, 3
Affiliation  

The Childhood Asthma Prevention Study (CAPS) commenced in 1997 in Sydney, Australia, because of concern about the high and increasing prevalence of childhood asthma.1,2 Cross-sectional and ecological studies had shown that exposure to high concentrations of house dust mite (HDM) allergen and being sensitized to HDM were both associated with increased prevalence.3–6 Other studies had indicated that children who regularly consumed oily fish containing high levels of omega-3 fatty acids were less likely to have airway hyper-responsiveness (AHR) and asthma.7 Those who regularly consumed oils and spreads containing polyunsaturated fats with a higher proportion of omega-6 fatty acids had an increased prevalence of asthma-like symptoms.8

中文翻译:

队列资料:儿童哮喘预防研究(CAPS)

儿童哮喘预防研究(CAPS)于1997年在澳大利亚悉尼开始,原因是对儿童哮喘的高发和日益增长的担忧。1 2横断面和生态的研究表明,在暴露于高浓度的屋尘螨(HDM)的变应原的和被敏化到HDM均与发病率增加相关联。[3–6]其他研究表明,经常食用富含omega-3脂肪酸的油性鱼的儿童患气道高反应性(AHR)和哮喘的可能性较小。7那些经常食用油和含有多不饱和脂肪和omega-6脂肪酸比例较高的涂抹酱的人,哮喘样症状的患病率增加。8
更新日期:2018-05-25
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