The synthesis, isolation, and X-ray structure of a thioanisole-based trilithium complex are reported. On the basis of the double-lithiation strategy, two novel synthetic methodologies have been developed under mild reaction conditions (room temperature): (1) reactions of lithiated thioanisoles with nitriles give benzoisothiazoles via a [3 + 2]-type of approach with two new bond formations and (2) formation of benzothiophenes from thioanisoles and amides through a [4 + 1] pattern forming 4 new chemical bonds.

中文翻译：

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硫代苯甲醚双骨架化合物的制备和CH锂化/环化反应，可用于五元杂环

报道了基于硫代苯甲醚的三锂配合物的合成，分离和X射线结构。在双重锂化策略的基础上，在温和的反应条件（室温）下开发了两种新颖的合成方法：（1）锂硫代苯甲醚与腈的反应通过[3 + 2]型方法得到苯并异噻唑，其中两种新的键形成和（2）通过[4 +1]模式由硫代苯甲醚和酰胺形成苯并噻吩，形成4个新的化学键。