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A Redox‐Based Superoxide Generation System Using Quinone/Quinone Reductase
ChemBioChem ( IF 3.2 ) Pub Date : 2018-06-26 , DOI: 10.1002/cbic.201800071
Shailesh Kumar Singh 1 , Syed Masood Husain 1
Affiliation  

Creating superspecies: A redox‐based, enzyme‐catalyzed system for superoxide (O2.−) generation is achieved through autoxidation of hydroquinone via semiquinone. To convert quinone to hydroquinone, a quinone/quinone reductase system is used. The system not only recycles quinones, which have superior water solubility, but also uses enzymes that are heterologously expressed.
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中文翻译:

基于醌/奎酮还原酶的基于氧化还原的超氧化物生成系统

创造超级物种:通过对苯二酚通过半醌的自氧化,实现了基于氧化还原的酶催化的超氧化物(O 2 .-)生成系统。为了将醌转化为氢醌,使用了醌/醌还原酶系统。该系统不仅可以回收水溶性优异的醌,而且还可以使用异源表达的酶。
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更新日期:2018-06-26
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