The C-1, C-7, and C-11 positions of pyripyropene A were chemically modified to improve the insecticidal activity. Some derivatives showed higher insecticidal activities against aphids than pyripyropene A. In particular, the derivative 5c, which possesses three cyclopropyl carbonyl groups at the C-1, C-7, and C-11 positions, had excellent insecticidal activity levels in field and laboratory trials.

中文翻译：

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吡啶并茂衍生物的合成和杀虫功效主要集中在C-1，C-7和C-11位的取代基上。

吡啶并戊二烯A的C-1，C-7和C-11位置经过化学修饰以提高杀虫活性。一些衍生物对蚜虫的杀虫活性高于吡啶并戊烯A。特别是，在C-1，C-7和C-11位置具有三个环丙基羰基的衍生物5c在野外和实验室均具有出色的杀虫活性。审判。