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Formation of capsaicin loaded nanoemulsions with high pressure homogenization and ultrasonication
LWT - Food Science and Technology ( IF 6 ) Pub Date : 2018-05-19 , DOI: 10.1016/j.lwt.2018.05.043
Elif Akbas , Betul Soyler , Mecit Halil Oztop

Nanoemulsions could increase the bioavailability of lipophilic compounds. In this study, nanoemulsions were obtained by high pressure homogenization and ultrasonication using capsaicin (oleoresin capsicum) (2 g/100g) in the oil phase and Tween 80 (2 g/100g), glycerol (0-50 g/100g) in the aqueous phase at pH 7.4 and 3.8. Mean droplet sizes below 65 nm were obtained with ultrasonication. Translucent nanoemulsions with minimum 79% efficiencies were obtained with high pressure homogenization. Pressurized nanoemulsions reduced Staphylococcus aureus and Escherichia coli population up to 5.89 and 2.79 log respectively at pH 7.4. The addition of glycerol resulted in almost transparent, bright red colored nanoemulsions. Therefore, capsaicin nanoemulsions showing good antimicrobial activity could be obtained by high pressure homogenization, whereas ultrasonication mostly helped to improve physical properties such as particle size and color.



中文翻译:

高压均质和超声处理形成辣椒素负载纳米乳液

纳米乳剂可以增加亲脂性化合物的生物利用度。在这项研究中,通过在油相中使用辣椒素(油性辣椒素)(2 g / 100g)和在吐温80中使用吐温80(2 g / 100g)和甘油(0-50 g / 100g),通过高压均质化和超声处理获得纳米乳液。 pH 7.4和3.8的水相。通过超声处理获得低于65nm的平均液滴尺寸。通过高压均质化获得了最低效率为79%的半透明纳米乳液。加压纳米乳液可减少金黄色葡萄球菌大肠杆菌pH 7.4时分别达到5.89和2.79 log的种群。甘油的加入产生了几乎透明的,鲜红色的纳米乳剂。因此,可以通过高压均质获得显示出良好抗菌活性的辣椒素纳米乳剂,而超声处理主要有助于改善物理性质,例如粒度和颜色。

更新日期:2018-05-19
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