A Ru‐catalyzed intramolecular hydroarylation of arenes in an aqueous medium is presented herein. With the aid of methyl phenyl sulfoximine or an amide directing group, this atom‐efficient hydroarylation of arenes ensued dihydrobenzofuran derivatives. Sequential double hydroarylation of arene motifs resulted in highly peripheral‐decorated heterocycles. Deuterium labeling studies and control experiments offer valuable information in understanding the reactivity and the mechanistic data.

中文翻译：

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钌催化水中芳烃的分子内氢芳基化

本文介绍了Ru在水性介质中催化的芳烃分子内氢芳基化反应。借助甲基苯基亚砜亚胺或一个酰胺指导基团，芳烃的这种原子有效的氢芳基化反应产生了二氢苯并呋喃衍生物。芳烃基序的顺序双氢芳基化导致高度外围装饰的杂环。氘标记研究和对照实验为理解反应性和机理数据提供了有价值的信息。