Ancient genomes document multiple waves of migration in Southeast Asian prehistory,Science

当前位置： X-MOL 学术 › Science › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Ancient genomes document multiple waves of migration in Southeast Asian prehistory
Science ( IF 56.9 ) Pub Date : 2018-05-17 , DOI: 10.1126/science.aat3188
Mark Lipson ₁ , Olivia Cheronet _{2,

3,

4} , Swapan Mallick _{1,

5} , Nadin Rohland ₁ , Marc Oxenham ₆ , Michael Pietrusewsky ₇ , Thomas Oliver Pryce _{8,

9,

10} , Anna Willis ₁₁ , Hirofumi Matsumura ₁₂ , Hallie Buckley ₁₃ , Kate Domett ₁₄ , Giang Hai Nguyen ₁₅ , Hoang Hiep Trinh ₁₅ , Aung Aung Kyaw ₁₆ , Tin Tin Win ₁₆ , Baptiste Pradier ₉ , Nasreen Broomandkhoshbacht _{1,

17} , Francesca Candilio _{18,

19} , Piya Changmai ₂₀ , Daniel Fernandes _{2,

3,

21} , Matthew Ferry _{1,

17} , Beatriz Gamarra _{3,

4} , Eadaoin Harney _{1,

17} , Jatupol Kampuansai _{22,

23} , Wibhu Kutanan ₂₄ , Megan Michel _{1,

17} , Mario Novak _{3,

25} , Jonas Oppenheimer _{1,

17} , Kendra Sirak _{3,

26} , Kristin Stewardson _{1,

17} , Zhao Zhang ₁ , Pavel Flegontov _{20,

27} , Ron Pinhasi _{2,

3} , David Reich _{1,

5,

17}

Affiliation

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Department of Anthropology, University of Vienna, 1090 Vienna, Austria.
Earth Institute, University College Dublin, Dublin 4, Ireland.
School of Archaeology, University College Dublin, Dublin 4, Ireland.
Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
School of Archaeology and Anthropology, Australian National University, Canberra, ACT 0200, Australia.
Department of Anthropology, University of Hawai‘i at Mānoa, Honolulu, Hawai‘i 96822, USA.
Centre National de la Recherche Scientifique, 75016 Paris, France.
UMR 7055 Préhistoire et Technologie, Université Paris Nanterre, 92023 Nanterre, France.
CEA/CNRS UMR 3685 NIMBE, 91191 Gif-sur-Yvette, France.
College of Arts, Society and Education, James Cook University, Townsville, Queensland 4811, Australia.
School of Health Science, Sapporo Medical University, Sapporo 060-8556, Japan.
Department of Anatomy, University of Otago, Dunedin 9054, New Zealand.
Division of Tropical Health and Medicine, College of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811, Australia.
Department of Prehistoric Archaeology, Vietnam Institute of Archaeology, Hanoi, Vietnam.
Department of Archaeology, Ministry of Religious Affairs and Culture, Mandalay, Myanmar.
Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
Soprintendenza Archeologia Belle Arti e Paesaggio per la Città Metropolitana di Cagliari e per le Province di Oristano e Sud Sardegna, 09124 Cagliari, Italy.
Physical Anthropology Section, University of Pennsylvania Museum of Archaeology and Anthropology, Philadelphia, PA 19104, USA.
Department of Biology and Ecology, Faculty of Science, University of Ostrava, 70103 Ostrava, Czech Republic.
CIAS, Department of Life Sciences, University of Coimbra, Coimbra 3000-456, Portugal.
Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Center of Excellence in Bioresources for Agriculture, Industry and Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Department of Biology, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.
Institute for Anthropological Research, 10000 Zagreb, Croatia.
Department of Anthropology, Emory University, Atlanta, GA 30322, USA.
Institute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 České Budějovice, Czech Republic.

Ancient migrations in Southeast Asia The past movements and peopling of Southeast Asia have been poorly represented in ancient DNA studies (see the Perspective by Bellwood). Lipson et al. generated sequences from people inhabiting Southeast Asia from about 1700 to 4100 years ago. Screening of more than a hundred individuals from five sites yielded ancient DNA from 18 individuals. Comparisons with present-day populations suggest two waves of mixing between resident populations. The first mix was between local hunter-gatherers and incoming farmers associated with the Neolithic spreading from South China. A second event resulted in an additional pulse of genetic material from China to Southeast Asia associated with a Bronze Age migration. McColl et al. sequenced 26 ancient genomes from Southeast Asia and Japan spanning from the late Neolithic to the Iron Age. They found that present-day populations are the result of mixing among four ancient populations, including multiple waves of genetic material from more northern East Asian populations. Science, this issue p. 92, p. 88; see also p. 31 Ancient DNA data shed light on the past 4000 years of Southeast Asian genetic history. Southeast Asia is home to rich human genetic and linguistic diversity, but the details of past population movements in the region are not well known. Here, we report genome-wide ancient DNA data from 18 Southeast Asian individuals spanning from the Neolithic period through the Iron Age (4100 to 1700 years ago). Early farmers from Man Bac in Vietnam exhibit a mixture of East Asian (southern Chinese agriculturalist) and deeply diverged eastern Eurasian (hunter-gatherer) ancestry characteristic of Austroasiatic speakers, with similar ancestry as far south as Indonesia providing evidence for an expansive initial spread of Austroasiatic languages. By the Bronze Age, in a parallel pattern to Europe, sites in Vietnam and Myanmar show close connections to present-day majority groups, reflecting substantial additional influxes of migrants.

更新日期：2018-05-17

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>