To the Editor—We thank Drs Buonfrate and Bisoffi for reading our article. Our small long-term observational follow-up study included 21 ivermectin-treated patients; 14 of them presented with reactivation by larvae observation [1]. A few years ago, our group reported that 1 of 10 patients with strongyloidiasis showed a persistent increase in eosinophil counts beginning 4 months after ivermectin treatment, reaching values of eosinophilia after the 10th month of follow-up [2]. According to this observation, 3–4 consecutive stool samples were exhaustively examined by agar plate culture (APC). In the third test, at the 10th month, Strongyloides stercoralis larvae were detected [2].

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回复Buonfrate和Bisoffi

致编辑-感谢Buonfrate博士和Bisoffi女士阅读我们的文章。我们的小型长期观察性随访研究包括21例伊维菌素治疗的患者。其中有14例通过幼虫观察而重新激活[1]。几年前，我们的小组报告说，在伊维菌素治疗后4个月开始，每10名强弓形虫病患者中就有1例嗜酸性粒细胞计数持续增加，在随访的第10个月后达到嗜酸性粒细胞计数[2]。根据该观察结果，通过琼脂平板培养（APC）彻底检查了3-4个连续的粪便样品。在第三个测试中，即第10个月，检测到了圆线虫stercoralis幼虫[2]。