We retrospectively assessed breakthrough invasive fungal infections (b-IFIs) in 100 consecutive patients with leukemia receiving single-agent isavuconazole; 13 had documented b-IFIs (candidiasis in 6, mucormycosis in 4). All b-IFIs were observed in patients with prolonged neutropenia and active leukemia.

中文翻译：

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接受艾沙康唑治疗的白血病患者出现突破性真菌感染

我们回顾性评估了 100 名连续接受单药艾沙康唑治疗的白血病患者的突破性侵袭性真菌感染 (b-IFI)；13 人患有 b-IFI（6 人患有念珠菌病，4 人患有毛霉菌病）。所有 b-IFI 均在患有长期中性粒细胞减少症和活动性白血病的患者中观察到。