Excellent solution-based gelators are generally advantaged by a short gelling time and low gelator loading when compared to powder gelators having a structurally similar backbone. However, high solubility in essentially non-toxic carrier solvents such as ethanol and ethyl acetate still presents a significant bottleneck to their commercial use in large-scale treatment of marine oil spills. In this work, we present a molecular strategy for rapid evolution of a highly soluble POSG (6a-Phe-C4) with high gelling ability toward seven types of (un)weathered crude oils at room temperature. Discovered from a total of 116 PSOGs, gelator 6a-Phe-C4 possesses a record-high solubility of 380 mg mL⁻¹ in a mixed carrier solvent (ethyl acetate : ethanol = 3 : 2, v/v). This value is even higher than the solubility of 359 mg mL⁻¹ for NaCl in water. Moreover, its gelling abilities toward two types of heavy crude oils and three types of highly weathered crude oils at room temperature are much better than those of the best solution-based gelator F-Leu-C4 recently developed by us. As such, the amounts of carrier solvent required now can be reduced markedly to 1.8–5.7 vol% of oil to be gelled, which are 0.4–5.8 times smaller than those needed for F-Leu-C4.

中文翻译：

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具有高胶凝能力的高溶解性相选择有机胶凝剂的组合鉴定，可用于原油胶凝†

与具有结构相似主链的粉末胶凝剂相比，优秀的基于溶液的胶凝剂通常具有较短的胶凝时间和较低的胶凝剂负载优势。但是，在基本上无毒的载体溶剂（例如乙醇和乙酸乙酯）中的高溶解度仍然是其在大规模处理海洋溢油中的商业用途的重大瓶颈。在这项工作中，我们提出了一种分子策略，可在室温下快速发展具有高胶凝能力的高溶解性POSG（6a-Phe-C4）向七种类型的未风化原油。从总共116种PSOG中发现，胶凝剂6a-Phe-C4具有380 mg mL ^-1的创纪录高溶解度在混合载体溶剂中（乙酸乙酯：乙醇＝ 3∶2，v / v）。该值甚至高于对于NaCl在水中的359 mg mL ^-1的溶解度。此外，它在室温下对两种重质原油和三种高风化原油的胶凝能力比我们最近开发的最佳溶液基胶凝剂F-Leu-C4的胶凝能力要好得多。因此，现在可以将所需的载体溶剂量显着减少至要胶凝的油的1.8-5.7％（体积），这比F-Leu-C4所需的量小0.4-5.8倍。