Suzuki–Miyaura coupling of nonbenzylic α‐(acylamino)alkylboron compounds with aryl halides is established. A Pd/PCy₂Ph catalyst promotes the reaction efficiently at 145 °C. The reaction of enantioenriched α‐(acylamino)alkylboron compounds affords chiral 1‐arylalkylamides in high enantiospecificity and inversion of configuration.

中文翻译：

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非苄基α-（酰基氨基）烷基硼酸衍生物的对映体特异性Suzuki-Miyaura偶联

建立了非苄基α-（酰基氨基）烷基硼化合物与芳基卤化物的Suzuki-Miyaura偶联。Pd / PCy ₂ Ph催化剂可在145°C的条件下有效地促进反应。富含对映体的α-（酰基氨基）烷基硼化合物的反应可提供高对映体特异性和构型反转的手性1-芳基烷基酰胺。