当前位置: X-MOL 学术ChemBioChem › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Cyclic Peptides for Efficient Detection of Collagen
ChemBioChem ( IF 3.2 ) Pub Date : 2018-06-21 , DOI: 10.1002/cbic.201800166
Koh K. Takita 1 , Kazunori K. Fujii 1 , Tetsuya Kadonosono 2 , Ryo Masuda 1 , Takaki Koide 1
Affiliation  

Detection of collagen: The cyclic collagen‐mimetic peptide (cCMP) hybridizes efficiently with denatured portions of the collagen triple helix. Such cCMP compounds can be used to detect various types of collagen polypeptide by western blotting or, with fluorescein‐labeled cCMP, to visualize damaged collagen fibrils secreted from cultured cells and folding intermediates in the endoplasmic reticulum.
image


中文翻译:

高效检测胶原蛋白的环肽

胶原蛋白的检测:环状胶原模拟肽(cCMP)与胶原三螺旋的变性部分有效杂交。此类cCMP化合物可用于通过蛋白质印迹法检测各种类型的胶原蛋白多肽,或与荧光素标记的cCMP结合使用,以可视化从培养细胞分泌的受损胶原蛋白原纤维和内质网中的折叠中间体。
图像
更新日期:2018-06-21
down
wechat
bug