Caesaldecins A and B (1a/1b), a pair of epimeric cassane-type diterpenoids containing an ether linkage between C-6 and C-20 and an α,β-butenolide ring in the northern hemisphere, were isolated from the leaves of the medicinal plant Caesalpinia decapetala (Roth) Alston, along with a new labdane-type diterpenoid, termed as 8(17),11(Z),13(E)-trien-15,18-dioic acid (2). Structures of 1 and 2 were established by extensive spectroscopic analyses, including HRESIMS, 1D and 2D NMR, and electronic circular dichroism (ECD) calculations. The in vitro antibacterial and inhibitory activities against a panel of bacteria and cancer cell lines were evaluated, respectively. Compound 2 displayed moderate antibacterial activity against the methicillin-resistant Staphylococcus aureus subsp. aureus (MRSA) with an MIC₅₀ value of 5.99 μg mL⁻¹.

从叶子中分离出一对Caesaldecins A和B（1 a / 1 b），它们是一对在C-6和C-20之间具有醚键并在北半球具有α，β-丁烯内酯环的游离木薯型二萜。药用植物Caesalpinia decapetala（Roth）Alston，以及一种新的拉丹型双萜，称为8（17），11（Z），13（E）-trien-15,18-二酸（2）。1和2的结构是通过广泛的光谱分析确定的，包括HRESIMS，1D和2D NMR以及电子圆二色性（ECD）计算。该在体外分别评估了对一组细菌和癌细胞系的抗菌和抑制活性。化合物2对耐甲氧西林的金黄色葡萄球菌亚种表现出中等的抗菌活性。金黄色葡萄球菌（MRSA）的MIC ₅₀值为5.99μgmL ^-1。