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Magnetic conjugated polymer nanoparticles doped with a europium complex for biomedical imaging†
Photochemical & Photobiological Sciences ( IF 3.1 ) Pub Date : 2018-05-10 00:00:00 , DOI: 10.1039/c7pp00402h
E. Kemal 1, 2, 3, 4, 5 , R. Peters 1, 2, 3, 4, 5 , S. Bourke 1, 2, 3, 4, 5 , S. Fairclough 1, 2, 3, 4, 5 , P. Bergstrom-Mann 1, 2, 3, 4, 5 , D. M. Owen 1, 2, 3, 4, 5 , L. Sandiford 1, 2, 3, 4, 5 , L. A. Dailey 6, 7, 8, 9 , M. Green 1, 2, 3, 4, 5
Affiliation  

Self-assembling conjugated polymer nanoparticles containing PVK and PLGA-PEG as a matrix polymer were doped with both a luminescent rare-earth complex and magnetic nanoparticles (SPIONs), giving rise to materials that are both luminescent and magnetic. Nanoparticle sizes ranged from 80–110 nm without SPIONs and showed an increase in size (200–1000 nm) with additional SPION content (11–54%). Quantum yields (QYs) of 24% and 18% were measured for systems without and with 11% SPIONs, respectively. Optical properties were stable and suitable for biological imaging applications.

中文翻译:

掺有complex配合物的磁性共轭聚合物纳米颗粒用于生物医学成像

含有PVK和PLGA-PEG作为基质聚合物的自组装共轭聚合物纳米颗粒既掺杂了发光稀土配合物,又掺杂了磁性纳米颗粒(SPIONs),从而产生了既发光又磁性的材料。没有SPIONs的纳米颗粒尺寸范围为80-110 nm,并且在增加SPION含量(11-54%)的情况下显示尺寸增加(200-1000 nm)。对于没有和有11%SPION的系统,测得的量子产率(QYs)分别为24%和18%。光学性质稳定并且适合生物成像应用。
更新日期:2018-05-10
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