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Social niche shapes social behavior and cortisol concentrations during adolescence in female guinea pigs Horm. Behav. (IF 3.5) Pub Date : 2024-04-11 Taylor L. Rystrom, S. Helene Richter, Norbert Sachser, Sylvia Kaiser
Individualized social niches arise in social groups, resulting in divergent social behavior profiles among group members. During sensitive life phases, the individualized social niche can profoundly impact the development of social behavior and associated phenotypes such as hormone (e.g. cortisol) concentrations. Focusing on adolescence, we investigated the relationship between the individualized social
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Generalization of a positive-feature interoceptive morphine occasion setter across the rat estrous cycle Horm. Behav. (IF 3.5) Pub Date : 2024-04-06 Davin R. Peart, Ella V. Claridge, Jessica M. Karlovcec, Rita El Azali, Kathleen E. LaDouceur, Anita Sikic, Abina Thomas, Adiia P. Stone, Jennifer E. Murray
Interoceptive stimuli elicited by drug administration acquire conditioned modulatory properties of the induction of conditioned appetitive behaviours by exteroceptive cues. This effect may be modeled using a drug discrimination task in which the drug stimulus is trained as a positive-feature (FP) occasion setter (OS) that disambiguates the relation between an exteroceptive light conditioned stimulus
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Sex differences in responses to aggressive encounters among California mice Horm. Behav. (IF 3.5) Pub Date : 2024-04-06 Jace X. Kuske, Alexandra Serna Godoy, Alison V. Ramirez, Brian C. Trainor
Despite how widespread female aggression is across the animal kingdom, there remains much unknown about its neuroendocrine mechanisms, especially in females that engage in aggression outside the peripartum period. Although the impact of aggressive experience on steroid hormone responses have been described, little is known about the impact of these experiences on female behavior or the subsequent neuropeptide
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Effects of the combination of chronic unpredictable stress and environmental enrichment on anxiety-like behavior assessed using the elevated plus maze in Swiss male mice: Hypothalamus-Pituitary-Adrenal Axis-mediated mechanisms Horm. Behav. (IF 3.5) Pub Date : 2024-04-04 Ariadne Elisa Belo-Silva, Nivea Karla de Gusmão Taveiros Silva, Priscila Marianno, Gabriel de Araújo Costa, Veridiana Petenati da Rovare, Alexis Bailey, Carolina Demarchi Munhoz, Leonardo Santana Novaes, Rosana Camarini
Environmental enrichment (EE) is a paradigm that offers the animal a plethora of stimuli, including physical, cognitive, sensory, and social enrichment. Exposure to EE can modulate both anxiety responses and plasma corticosterone. In this study, our objective was to explore how chronic unpredictable stress (CUS) impacts anxiety-related behaviors in male Swiss mice raised in EE conditions. Additionally
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Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex Horm. Behav. (IF 3.5) Pub Date : 2024-03-23 Wenjuan Hou, Huan Ma, Caihong Huang, Yin Li, Lu Li, Lizi Zhang, Yishan Qu, Yufeng Xun, Qixuan Yang, Zhixiong He, Fadao Tai
Paternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior
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Letrozole delays acquisition of water maze task in female BALB/c mice: Possible involvement of anxiety Horm. Behav. (IF 3.5) Pub Date : 2024-03-21 Jacek Mamczarz, Malcolm Lane, Istvan Merchenthaler
Letrozole, an aromatase inhibitor preventing estrogen synthesis from testosterone, is used as an adjuvant therapy in estrogen receptor-positive breast cancer patients. However, like other aromatase inhibitors, it induces many side effects, including impaired cognition. Despite its negative effect in humans, results from animal models are inconsistent and suggest that letrozole can either impair or
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Early life conditions reduce similarity between reproductive partners in HPA axis response to stress Horm. Behav. (IF 3.5) Pub Date : 2024-03-20 Buddhamas P. Kriengwatana, Christopher J. Marshall, Tyler Stevenson, Pat Monaghan
Social environments modulate endocrine function, yet it is unclear whether individuals can become like their social partners in how they physiologically respond to stressors. This social transmission of hypothalamic-pituitary-adrenal (HPA) axis reactivity could have long-term consequences for health and lifespan of individuals if their social partners react to stressors with an exaggerated HPA axis
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Androgen regulation of behavioral stress responses and the hypothalamic-pituitary-adrenal axis Horm. Behav. (IF 3.5) Pub Date : 2024-03-18 Damian G. Zuloaga, Jennifer J. Lafrican, Kristen L. Zuloaga
Testosterone is a powerful steroid hormone that can impact the brain and behavior in various ways, including regulating behavioral and neuroendocrine (hypothalamic-pituitary-adrenal (HPA) axis) stress responses. Early in life androgens can act to alter development of brain regions associated with stress regulation, which ultimately impacts the display of stress responses later in life. Adult circulating
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The paradox of spring: Thyroid and glucocorticoid responses to cold temperatures and food availability in free living Carneddau ponies Horm. Behav. (IF 3.5) Pub Date : 2024-03-18 Jessica Granweiler, Jurgi Cristóbal-Azkarate, Nathan Morton, Rupert Palme, Susanne Shultz
In seasonal environments, maintaining a constant body temperature poses challenges for endotherms. Cold winters at high latitudes, with limited food availability, create opposing demands on metabolism: upregulation preserves body temperature but depletes energy reserves. Examining endocrine profiles, such as thyroid hormone triiodothyronine (T3) and glucocorticoids (GCs), proxies for changes in metabolic
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Prolactin promotes the recruitment of main olfactory bulb cells and enhances the behavioral exploration toward a socio-sexual stimulus in female mice Horm. Behav. (IF 3.5) Pub Date : 2024-03-15 Viridiana Cerbantez-Bueno, Verónica Viñuela-Berni, Daniel Eduardo Muñoz-Mayorga, Teresa Morales, Rebeca Corona
Olfactory communication is triggered by pheromones that profoundly influence neuroendocrine responses to drive social interactions. Two principal olfactory systems process pheromones: the main and the vomeronasal or accessory system. Prolactin receptors are expressed in both systems suggesting a participation in the processing of olfactory information. We previously reported that prolactin participates
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Conditioned preferences: Gated by experience, context, and endocrine systems Horm. Behav. (IF 3.5) Pub Date : 2024-03-15 Patrick K. Monari, Emma R. Hammond, Xin Zhao, Alyse N. Maksimoski, Radmila Petric, Candice L. Malone, Lauren V. Riters, Catherine A. Marler
Central to the navigation of an ever-changing environment is the ability to form positive associations with places and conspecifics. The functions of location and social conditioned preferences are often studied independently, limiting our understanding of their interplay. Furthermore, a de-emphasis on natural functions of conditioned preferences has led to neurobiological interpretations separated
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Glucocorticoid response to naturalistic interactions between children and dogs Horm. Behav. (IF 3.5) Pub Date : 2024-03-13 Gitanjali E. Gnanadesikan, Elizabeth Carranza, Katherine M. King, Abigail C. Flyer, Gianna Ossello, Paige G. Smith, Netzin G. Steklis, H. Dieter Steklis, Jessica J. Connelly, Melissa Barnett, Nancy Gee, Stacey Tecot, Evan L. MacLean
Although research has shown that pets appear to provide certain types of social support to children, little is known about the physiological bases of these effects, especially in naturalistic contexts. In this study, we investigated the effect of free-form interactions between children (ages 8–10 years) and dogs on salivary cortisol concentrations in both species. We further investigated the role of
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A tale of two males: Behavioral and neural mechanisms of alternative reproductive tactics in midshipman fish Horm. Behav. (IF 3.5) Pub Date : 2024-03-12 Andrew H. Bass
An amalgam of investigations at the interface of neuroethology and behavioral neuroendocrinology first established the most basic behavioral, neuroanatomical, and neurophysiological characters of vocal-acoustic communication morphs in the plainfin midshipman fish, Girard. This foundation has led, in turn, to the repeated demonstration that neuro-behavioral mechanisms driving reproductive-related, vocal-acoustic
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Fathers and sons, mothers and daughters: Sex-specific genetic architecture for fetal testosterone in a wild mammal Horm. Behav. (IF 3.5) Pub Date : 2024-03-06 Ruth Fishman, Simona Kralj-Fišer, Sivan Marglit, Lee Koren, Yoni Vortman
Testosterone plays a critical role in mediating fitness-related traits in many species. Although it is highly responsive to environmental and social conditions, evidence from several species show a heritable component to its individual variation. Despite the known effects that in utero testosterone exposure have on adult fitness, the heritable component of individual testosterone variation in fetuses
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The role of exogenous testosterone and social environment on the expression of sociosexuality and status-seeking behaviors in young Chilean men Horm. Behav. (IF 3.5) Pub Date : 2024-03-06 Pablo Polo, Gabriela Fajardo, Jose Antonio Muñoz-Reyes, Nohelia T. Valenzuela, Montserrat Belinchón, Oriana Figueroa, Ana Fernández-Martínez, Marcel Deglín, Miguel Pita
Testosterone plays an important role as a social hormone. Current evidence suggests that testosterone is positively related to sociosexuality increasing the psychological attitudes toward investing in short-term versus long-term mating and promotes status-seeking behaviors both by dominance and prestige. In addition, the social environment may play an important role in the expression of mating effort
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Social regulation of arginine vasopressin and oxytocin systems in a wild group-living fish Horm. Behav. (IF 3.5) Pub Date : 2024-03-06 Brett M. Culbert, Isaac Y. Ligocki, Matthew G. Salena, Marian Y.L. Wong, Ian M. Hamilton, Nicholas J. Bernier, Sigal Balshine
The neuropeptides arginine vasopressin (AVP) and oxytocin (OXT) are key regulators of social behaviour across vertebrates. However, much of our understanding of how these neuropeptide systems interact with social behaviour is centred around laboratory studies which fail to capture the social and physiological challenges of living in the wild. To evaluate relationships between these neuropeptide systems
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Estrogenic influences on agonistic behavior in teleost fishes Horm. Behav. (IF 3.5) Pub Date : 2024-03-06 Katherine A. Stennette, John R. Godwin
Teleost fishes show an extraordinary diversity of sexual patterns, social structures, and sociosexual behaviors. Sex steroid hormones are key modulators of social behaviors in teleosts as in other vertebrates and act on sex steroid receptor-containing brain nuclei that form the evolutionarily conserved vertebrate social behavior network (SBN). Fishes also display important differences relative to tetrapod
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Low dose of propyl-pyrazole-triol, an agonist of estrogen receptor alpha, administration stimulates the Coolidge effect in fadrozole-treated male rats Horm. Behav. (IF 3.5) Pub Date : 2024-03-05 P. Hanna C. Corre, Joanna M. Mainwaring, K. Kenn Z. Peralta, P. Mark Lokman, Robert Porteous, Erik Wibowo
Estrogen receptor (ER) α is involved in male sexual function. Here, we aim to investigate how ERα activation influences sexual satiety and the Coolidge effect (i.e., when a rat, that has reached sexual satiety, experiences an increased arousal after exposure to a novel sexual partner) in estrogen-deprived male rats. Male rats (8 per group) were treated daily for 29 days with either saline (Control
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G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice Horm. Behav. (IF 3.5) Pub Date : 2024-03-01 Gustavo D.B. Machado, Alexis L. Schnitzler, Aaron W. Fleischer, Sarah B. Beamish, Karyn M. Frick
Studies in ovariectomized (OVX) female rodents suggest that G protein-coupled estrogen receptor (GPER) is a key regulator of memory, yet little is known about its importance to memory in males or the cellular mechanisms underlying its mnemonic effects in either sex. In OVX mice, bilateral infusion of the GPER agonist G-1 into the dorsal hippocampus (DH) enhances object recognition and spatial memory
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Neural thyroid hormone metabolism integrates seasonal changes in environmental temperature with the neuroendocrine reproductive axis Horm. Behav. (IF 3.5) Pub Date : 2024-02-28 Deborah I. Lutterschmidt, Kalera Stratton, Treven J. Winters, Stephanie Martin, Lauren J. Merlino
We asked if environmental temperature alters thyroid hormone metabolism within the hypothalamus, thereby providing a neuroendocrine mechanism by which temperature could be integrated with photoperiod to regulate seasonal rhythms. We used immunohistochemistry to assess the effects of low-temperature winter dormancy at 4 °C or 12 °C on thyroid-stimulating hormone (TSH) within the infundibulum of the
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The effects of diazepam on fear extinction in nulliparous and primiparous female rats Horm. Behav. (IF 3.5) Pub Date : 2024-02-28 Jodie E. Pestana, Tasfia Kabir, Bronwyn M. Graham
Benzodiazepines undermine the success of exposure therapy in humans with anxiety disorders, and impair the long-term memory of fear extinction (the laboratory basis of exposure therapy) in rodents. However, most rodent studies on fear extinction and benzodiazepines have been conducted in male rodents. In female rodents, the estrous cycle influences the consolidation of fear extinction memories and
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Why biodiversity matters in the lab Horm. Behav. (IF 3.5) Pub Date : 2024-02-24 Richmond Thompson, Yvon Delville, Christine Lattin
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Repeated exposure to physiologically effective doses of contraceptive hormones ethinyl estradiol or levonorgestrel do not alter the reinforcing effects of a brief visual stimulus in ovary-intact rats Horm. Behav. (IF 3.5) Pub Date : 2024-02-22 Kathleen R. McNealy, Matthew W. Oevermann, MacKenzie L. Knabel, Anna Fitzwater, Cassandra D. Gipson, Scott T. Barrett, Rick A. Bevins
Estradiol and progesterone potentiate and attenuate reward processes, respectively. Despite these well-characterized effects, there is minimal research on the effects of synthetic estrogens (e.g., ethinyl estradiol, or EE) and progestins (e.g., levonorgestrel, or LEVO) contained in clinically-utilized hormonal contraceptives. The present study characterized the separate effects of repeated exposure
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How new communication behaviors evolve: Androgens as modifiers of neuromotor structure and function in foot-flagging frogs Horm. Behav. (IF 3.5) Pub Date : 2024-02-21 Lisa A. Mangiamele, AllexAndrya Dawn, Kerry M. LeCure, Gina E. Mantica, Riccardo Racicot, Matthew J. Fuxjager, Doris Preininger
How diverse animal communication signals have arisen is a question that has fascinated many. frogs have been a model system used for three decades to reveal insights into the neuroendocrine mechanisms and evolution of vocal diversity. Due to the ease of studying central nervous system control of the laryngeal muscles in vitro, has helped us understand how variation in vocal communication signals between
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The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat Horm. Behav. (IF 3.5) Pub Date : 2024-02-17 Sofia Zelleroth, Frida Stam, Erik Nylander, Ellinor Kjellgren, Johan Gising, Mats Larhed, Alfhild Grönbladh, Mathias Hallberg
Long-term use of anabolic androgenic steroids (AAS) in supratherapeutic doses is associated with severe adverse effects, including physical, mental, and behavioral alterations. When used for recreational purposes several AAS are often combined, and in scientific studies of the physiological impact of AAS either a single compound or a cocktail of several steroids is often used. Because of this, steroid-specific
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Thyroid hormone concentrations in female baboons: Metabolic consequences of living in a highly seasonal environment Horm. Behav. (IF 3.5) Pub Date : 2024-02-15 Laurence R. Gesquiere, Christine Adjangba, Tim L. Wango, Vivian K. Oudu, Raphael S. Mututua, J. Kinyua Warutere, I. Long’ida Siodi, Fernando A. Campos, Elizabeth A. Archie, A. Catherine Markham, Susan C. Alberts
How female mammals adapt metabolically in response to environmental variation remains understudied in the wild, because direct measures of metabolic activity are difficult to obtain in wild populations. However, recent advances in the non-invasive measurement of fecal thyroid hormones, triiodothyronine (T3), an important regulator of metabolism, provide an opportunity to understand how female baboons
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Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling Horm. Behav. (IF 3.5) Pub Date : 2024-02-14 Rashmi Patil, Urmila Aswar, Nishant Vyas
Cafeteria diet (CD) model for in-vivo studies mimics the western diet having imbalanced nutritional value, high caloric-density and palatability. Uncontrolled eating leads to the development of childhood obesity, poor self-esteem and depression due to its effects on brain development. Herbal supplements are novel inclusion in the management of obesity and mental well-being. Pterostilbene (PTE) found
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Delivery by cesarean section leads to heavier adult bodyweight in prairie voles (Microtus ochrogaster) Horm. Behav. (IF 3.5) Pub Date : 2024-02-13 William M. Kenkel, Sabreen Ahmed, Miranda Partie, Katelyn Rogers
Delivery by cesarean section now makes up 32.1 % of all births in the United States. Meta-analyses have estimated that delivery by cesarean section is associated with a > 50 % increased risk for childhood obesity by 5 years of age. While this association is independent of maternal obesity, breastfeeding, and heritable factors, studies in humans have been unable to test for a causal role of cesarean
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Effects of intrauterine position during gestation on specific endocrine and behavioral parameters that impact reproduction in domestic rabbits Horm. Behav. (IF 3.5) Pub Date : 2024-02-10 Lizet García-Fernández, David R. Chavira, Kurt Hoffman, Gabriela González-Mariscal
Prior studies from others, performed in a different breed, reported that doe rabbits developing between two male siblings (2 M) during gestation display characteristics indicative of masculinization: larger anogenital distance (AGD), larger submandibular glands, and higher chinning frequency than females with zero (0 M) or one (1 M) contiguous brothers. Similar effects are provoked by injecting androgens
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Odours of caterpillar-infested trees increase testosterone concentrations in male great tits Horm. Behav. (IF 3.5) Pub Date : 2024-02-09 Ségolène Delaitre, Marcel E. Visser, Kees van Oers, Samuel P. Caro
Trees release Herbivore-Induced Plant Volatiles (HIPVs) into the air in response to damage inflicted by insects. It is known that songbirds use those compounds to locate their prey, but more recently the idea emerged that songbirds could also use those odours as cues in their reproductive decisions, as early spring HIPVs may contain information about the seasonal timing and abundance of insects. We
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Special Issue: Highlights of SBN 2022 Horm. Behav. (IF 3.5) Pub Date : 2024-02-05 Farrah N. Madison, Nora H. Prior, Brian C. Trainor
Abstract not available
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Experimentally elevated corticosterone does not affect bacteria killing ability of breeding female tree swallows (Tachycineta bicolor) Horm. Behav. (IF 3.5) Pub Date : 2024-02-04 David A. Chang van Oordt, Conor C. Taff, Monique A. Pipkin, Thomas A. Ryan, Maren N. Vitousek
The immune system can be modulated when organisms are exposed to acute or chronic stressors. Glucocorticoids (GCs), the primary hormonal mediators of the physiological stress response, are suspected to play a crucial role in immune modulation. However, most evidence of stress-associated immunomodulation does not separate the effects of glucocorticoid-dependent pathways from those of glucocorticoid-independent
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A hamster model for stress-induced weight gain Horm. Behav. (IF 3.5) Pub Date : 2024-02-01 Kevin M. Moran, Yvon Delville
This review addresses the translational relevance of animal models of stress and their effects on body weight. In humans, stress, whether chronic or acute, has often been associated with increased food intake and weight gain. In view of the current obesity epidemic, this phenomenon is especially relevant. Such observations contrast with reports with commonly used laboratory animals, especially rats
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Selective attention towards infants in nulliparous women across the menstrual cycle Horm. Behav. (IF 3.5) Pub Date : 2024-02-01 Sarah K.C. Holtfrerich, Esther K. Diekhof
Research in women showed that testosterone is associated with decreased selective attention towards infant stimuli, which can be compensated for by oxytocin administration. In theory, caregiving behavior is thought to be mediated by oxytocin. Oxytocin binds to dopaminergic neurons and thus supposedly motivates aspects of caregiving through its influence on dopaminergic transmission. Most previous studies
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Social environment and anogenital distance length phenotype interact to explain testosterone levels in a communally rearing rodent: Part 2: The female side Horm. Behav. (IF 3.5) Pub Date : 2024-01-31 Loreto A. Correa, Antonia Aspillaga-Cid, Cecilia León, Carolyn M. Bauer, Juan Ramírez-Estrada, Loren D. Hayes, Mauricio Soto-Gamboa, Luis A. Ebensperger
Testosterone is known as a “male” hormone; however, females also synthetize testosterone, which influences female sexual and aggressive behavior. In female vertebrates, as in males, testosterone levels can vary seasonally. However, female testosterone levels may also be related with female anogenital distance (AGD) length phenotype (a proxy of prenatal androgen exposure), and the social group environment
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Leveraging the unique social organization of California mice to study circuit-specific effects of oxytocin on behavior Horm. Behav. (IF 3.5) Pub Date : 2024-01-27 Alyssa A. Lake, Brian C. Trainor
Oxytocin is a versatile neuropeptide that modulates many different forms of social behavior. Recent hypotheses pose that oxytocin enhances the salience of rewarding and aversive social experiences, and the field has been working to identify mechanisms that allow oxytocin to have diverse effects on behavior. Here we review studies conducted on the California mouse () that shed light on how oxytocin
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From pathology to pleasure: Reframing mechanistic studies on same-sex sexual behavior in primates Horm. Behav. (IF 3.5) Pub Date : 2024-01-25 Evan Cunningham, Marcela E. Benítez
Same-sex sexual behaviors (SSB) in primates have historically been studied as sexual perversions, evolutionary paradoxes, and hormone-driven pathologies. Researchers in recent decades have challenged these perspectives, yet some of the original biases still linger. In this paper, we examine how the study of endocrinological mechanisms in SSB has been influenced by the historical framework of pathology
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Social environment and anogenital distance length phenotype interact to explain testosterone levels in a communally rearing rodent: Part 1: The male side Horm. Behav. (IF 3.5) Pub Date : 2024-01-25 Loreto A. Correa, Antonia Aspillaga-Cid, Carolyn M. Bauer, Danna Silva-Álvarez, Cecilia León, Juan Ramírez-Estrada, Mauricio Soto-Gamboa, Loren D. Hayes, Luis A. Ebensperger
In vertebrates, male testosterone levels vary across the year being generally higher during the mating season relative to the offspring rearing season. However, male testosterone levels may also be associated with male anogenital distance (AGD) length (a proxy of prenatal androgen exposition), and influenced by the social group environment. In social species, it has been proposed that high levels of
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In your CORT: Corticosterone and its receptors in the brain underlie mate choosiness in female Cope's gray treefrogs (Hyla chrysoscelis) Horm. Behav. (IF 3.5) Pub Date : 2024-01-20 Mariana Rodriguez-Santiago, Annika Ruppert, Megan D. Gall, Kim Hoke, Mark A. Bee, Alexander T. Baugh
Selecting an attractive mate can involve trade-offs related to investment in sampling effort. Glucocorticoids like corticosterone (CORT) are involved in resolving energetic trade-offs. However, CORT is rarely studied in the context of mate choice, despite its elevated levels during reproductive readiness and the energetic transitions that characterize reproduction. Few systems are as well suited as
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Early life adversity accelerates hypothalamic drive of pubertal timing in female rats with associated enhanced acoustic startle Horm. Behav. (IF 3.5) Pub Date : 2024-01-18 Lauren Granata, Michaela Fanikos, Heather C. Brenhouse
Early life adversity in the form of childhood maltreatment in humans or as modeled by maternal separation (MS) in rodents is often associated with an earlier emergence of puberty in females. Earlier pubertal initiation is an example of accelerated biological aging and predicts later risk for anxiety in women, especially in populations exposed to early life trauma. Here we investigated external pubertal
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Hair cortisol and dehydroepiandrosterone and their associations with optimism and pessimism in older people Horm. Behav. (IF 3.5) Pub Date : 2024-01-08 Mariola Zapater-Fajarí, Isabel Crespo-Sanmiguel, Teresa Montoliu, Vanesa Hidalgo, Alicia Salvador
The cumulative negative effects of prolonged Hypothalamic-Pituitary-Adrenal axis (HPA axis) activation are associated with several age-related diseases. Some psychological traits such as optimism and pessimism have been shown to be related to both health and the stress response, although their relationship with the HPA axis is inconclusive. More stable HPA axis biomarkers, such as hair samples of cortisol
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Gender minority stress and diurnal cortisol profiles among transgender and gender diverse people in the United States Horm. Behav. (IF 3.5) Pub Date : 2024-01-07 L. Zachary DuBois, Jae A. Puckett, Dee Jolly, Sally Powers, Tian Walker, Debra A. Hope, Richard Mocarski, T. Zachary Huit, Brenna R. Lash, Natalie Holt, Allura Ralston, Makinna Miles, A. Capannola, Clove Tipton, Geeta Eick, Robert-Paul Juster
The field of behavioral neuroendocrinology has only begun to explore the lived experiences of transgender and gender diverse (TGD) people exposed to stigma. In light of escalating attacks and legislation targeting TGD people in the United States, it is crucial to examine the physiological pathways through which gender minority stressors become embodied, impact health, and contribute to health inequities
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Androgen receptors rapidly modulate non-breeding aggression in male and female weakly electric fish (Gymnotus omarorum) Horm. Behav. (IF 3.5) Pub Date : 2023-12-28 Guillermo Valiño, Kent Dunlap, Laura Quintana
The South American weakly electric fish, Gymnotus omarorum, displays territorial aggression year-round in both sexes. To examine the role of rapid androgen modulation in non-breeding aggression, we administered acetate cyproterone (CPA), a potent inhibitor of androgen receptors, to both male and females, just before staged agonistic interactions. Wild-caught fish were injected with CPA and, 30 min
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Thyroid hormones mediate the impact of early-life stress on ventral tegmental area gene expression and behavior Horm. Behav. (IF 3.5) Pub Date : 2023-12-22 Shannon N. Bennett, Austin B. Chang, Forrest D. Rogers, Parker Jones, Catherine Jensen Peña
Proper thyroid function is essential to the developing brain, including dopamine neuron differentiation, growth, and maintenance. Stress across the lifespan impacts thyroid hormone signaling and anxiety disorders and depression have been associated with thyroid dysfunction (both hypo- and hyper-active). However, less is known about how stress during postnatal development impacts thyroid function and
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Beyond the binary: Characterizing the relationships between sex and neuropeptide receptor binding density measures in the rat brain Horm. Behav. (IF 3.5) Pub Date : 2023-12-21 Daphna Joel, Caroline J. Smith, Alexa H. Veenema
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Levonorgestrel maintains goal-directed behavior in habit-trained intact female rats Horm. Behav. (IF 3.5) Pub Date : 2023-12-14 Sarah VonDoepp, Zaidan Mohammed, Russell Dougherty, Ella Hilton-Vanosdall, Sam Charette, Adina Kraus, Sarah Van Horn, Adrianna Quirk, Donna Toufexis
Hormonal contraceptives are utilized by millions of women worldwide. However, it remains unclear if these powerful endocrine modulators may alter cognitive function. Habit formation involves the progression of instrumental learning as it goes from being a conscious goal-directed process to a cue-driven automatic habitual motor response. Dysregulated goal and/or habit is implicated in numerous psychopathologies
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Impact of continuous testosterone exposure on reproductive physiology, activity, and pain-related behavior in young adult female rats Horm. Behav. (IF 3.5) Pub Date : 2023-12-13 Rebecca M. Craft, Christyne M. Sewell, Tessa M. Taylor, Mai Suong Vo, Kristen Delevich, Michael M. Morgan
Testosterone may reduce pain in cisgender women and transgender men. Rodents can provide a useful model for investigating physiological effects of hormone therapy. To this end, continuous-release testosterone or blank (placebo) capsules were implanted s.c. into young adult female rats, and three weeks later rats were either ovariectomized or sham-ovariectomized. Testosterone treatment that mimicked
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Toward understanding the endocrine regulation of diverse facultative migration strategies Horm. Behav. (IF 3.5) Pub Date : 2023-12-06 Heather E. Watts, Jamie M. Cornelius
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Early life adversity reduces affiliative behavior with a stressed cagemate and leads to sex-specific alterations in corticosterone responses in adult mice Horm. Behav. (IF 3.5) Pub Date : 2023-12-08 Jocelyn M. Breton, Zoey Cort, Camila Demaestri, Madalyn Critz, Samuel Nevins, Kendall Downend, Dayshalis Ofray, Russell D. Romeo, Kevin G. Bath
Experiencing early life adversity (ELA) alters stress physiology and increases the risk for developing psychiatric disorders. The social environment can influence dynamics of stress responding and buffer and/or transfer stress across individuals. Yet, the impact of ELA on sensitivity to the stress of others and social behavior following stress is unknown. Here, to test the impact of ELA on social and
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Corrigendum to “Menstrual cycle and exogenous attention toward emotional expressions” [Horm. Behav. 146 (2022) 105259] Horm. Behav. (IF 3.5) Pub Date : 2023-12-08 F. Álvarez, U. Fernández-Folgueiras, C. Méndez-Bértolo, D. Kessel, L. Carretié
Abstract not available
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A mouse model of oral contraceptive exposure: Depression, motivation, and the stress response Horm. Behav. (IF 3.5) Pub Date : 2023-12-06 Kristen M. Schuh, Jabir Ahmed, Esther Kwak, Cecilia X. Xu, Tronjay T. Davis, Chloe B. Aronoff, Natalie C. Tronson
Hormonal contraceptives, including oral contraceptives (OCs), regulate hormonal cycles and broadly affect physiological processes, including stress responsivity. Whereas many users describe overall improved mood, up to 10 % of OC users experience adverse effects, including depression and anxiety. Given the link between regulation of hypothalamic-pituitary-adrenal (HPA) axis, stress exposure, and risk
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Attention-deficit/hyperactivity disorder and the menstrual cycle: Theory and evidence Horm. Behav. (IF 3.5) Pub Date : 2023-11-30 Ashley G. Eng, Urveesha Nirjar, Anjeli R. Elkins, Yancey J. Sizemore, Krystina N. Monticello, Madeline K. Petersen, Sarah A. Miller, Jordan Barone, Tory A. Eisenlohr-Moul, Michelle M. Martel
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that exhibits striking sex differences in symptoms, prevalence, and associated problems across development. Etiological factors and mechanisms underlying these sex differences remain one of the most understudied aspects of this disorder. The current paper seeks to provide a novel theoretical framework for understanding
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From grouping and cooperation to menstruation: Spiny mice (Acomys cahirinus) are an emerging mammalian model for sociality and beyond Horm. Behav. (IF 3.5) Pub Date : 2023-11-24 Brandon A. Fricker, Aubrey M. Kelly
While spiny mice are primarily used as a model for Type II diabetes and for studying complex tissue regeneration, they are also an emerging model for a variety of studies examining hormones, behavior, and the brain. We began studying the spiny mouse to take advantage of their highly gregarious phenotype to examine how the brain facilitates large group-living. However, this unique rodent can be readily
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Comparative analysis of gonadal hormone receptor expression in the postnatal house mouse, meadow vole, and prairie vole brain Horm. Behav. (IF 3.5) Pub Date : 2023-11-22 Katherine A. Denney, Melody V. Wu, Simón(e) D. Sun, Soyoun Moon, Jessica Tollkuhn
The socially monogamous prairie vole (Microtus ochrogaster) and promiscuous meadow vole (Microtus pennsylvanicus) are closely related, but only prairie voles display long-lasting pair bonds, biparental care, and selective aggression towards unfamiliar individuals after pair bonding. These social behaviors in mammals are largely mediated by steroid hormone signaling in the social behavior network (SBN)
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The role of sex hormones, oral contraceptive use, and its parameters on visuospatial abilities, verbal fluency, and verbal memory. Horm. Behav. (IF 3.5) Pub Date : 2023-11-17 Lisa-Marie Davignon,Alexandra Brouillard,Robert-Paul Juster,Marie-France Marin
Sex hormones can cross the blood-brain barrier and access brain regions underlying higher-order cognition. Containing synthetic sex hormones, oral contraceptives (OC) have been found to modulate visuospatial and verbal abilities, though inconsistencies have been found in the literature. Among possible explanations, certain OC use parameters (progestin androgenicity, synthetic hormone levels, duration
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Noise and light pollution elicit endocrine responses in urban but not forest frogs. Horm. Behav. (IF 3.5) Pub Date : 2023-11-16 Judith A H Smit,Riet Vooijs,Peter Lindenburg,Alexander T Baugh,Wouter Halfwerk
Urban areas are characterised by the presence of sensory pollutants, such as anthropogenic noise and artificial light at night (ALAN). Animals can quickly adapt to novel environmental conditions by adjusting their behaviour, which is proximately regulated by endocrine systems. While endocrine responses to sensory pollution have been widely reported, this has not often been linked to changes in behaviour
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Sex diversity in the 21st century: Concepts, frameworks, and approaches for the future of neuroendocrinology. Horm. Behav. (IF 3.5) Pub Date : 2023-11-16 Kristina O Smiley,Kathleen M Munley,Krisha Aghi,Sara E Lipshutz,Tessa M Patton,Devaleena S Pradhan,Tessa K Solomon-Lane,Simón E D Sun
Sex is ubiquitous and variable throughout the animal kingdom. Historically, scientists have used reductionist methodologies that rely on a priori sex categorizations, in which two discrete sexes are inextricably linked with gamete type. However, this binarized operationalization does not adequately reflect the diversity of sex observed in nature. This is due, in part, to the fact that sex exists across
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Characterization of social hierarchy formation and maintenance in same-sex, group-housed male and female C57BL/6 J mice. Horm. Behav. (IF 3.5) Pub Date : 2023-11-15 Hannah D Fulenwider,Yangmiao Zhang,Andrey E Ryabinin
Social hierarchies are a prevalent feature of all animal groups, and an individual's rank within the group can significantly affect their overall health, typically at the greatest expense of the lowest-ranked individuals, or omegas. These subjects have been shown to exhibit various stress-related phenotypes, such as increased hypothalamic-pituitary axis activity and increased amygdalar corticotropin-releasing