Cooperative oncogenic effects resulting from the loss of PTEN and overexpression of MYC overcome the deleterious effects of endoplasmic reticulum stress not only to promote the growth of aggressive prostate cancer but also to expose a new therapy target for this disease (Nguyen et al., this issue).

中文翻译：

---

前列腺癌中的ER应激：可治疗地利用吗？

PTEN丢失和MYC过度表达导致的协同致癌作用克服了内质网应激的有害作用，不仅促进了侵袭性前列腺癌的生长，而且还揭示了该疾病的新治疗靶标（Nguyen等，本期）。