Three new natural products, including a new anthraquinone derivative isoversicolorin C (1), a new xanthone analog isosecosterigmatocystin (2), and a new amino acid derivative, glulisine A (3), along with six related metabolites (4-9) were isolated from the culture broth and mycelia extracts of the mangrove-derived endophytic fungus Aspergillus nidulans MA-143 under 0.1% ethanol stress. Their structures were elucidated by detailed analysis of their NMR spectra, ECD spectrum, and X-ray crystallographic experiments. Compounds 1 and 4 showed potent antibacterial activity against some of the tested microbes.

中文翻译：

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通过乙醇胁迫策略从红树林衍生的内生真菌Asdugillus nidulans中分离出抗菌蒽醌衍生物。

分离出了三种新的天然产物，包括新的蒽醌衍生物isoversicolorin C（1），新的蒽酮类似物异secosterigmatocystin（2）和新的氨基酸衍生物glulisine A（3），以及六种相关代谢物（4-9）。在0.1％乙醇胁迫下，从红树林衍生的内生真菌曲霉曲霉MA-143的培养液和菌丝体提取物中提取。通过对其NMR光谱，ECD光谱和X射线晶体学实验进行详细分析，阐明了它们的结构。化合物1和4对某些被测微生物表现出有效的抗菌活性。