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Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation
Theranostics ( IF 12.4 ) Pub Date : 2018-02-02 , DOI: 10.7150/thno.21745
Yun-Xin Lu , Qi-Nian Wu , Dong-liang Chen , Le-Zong Chen , Zi-Xian Wang , Chao Ren , Hai-yu Mo , Ya Chen , Hui Sheng , Ying-Nan Wang , Yun Wang , Jia-Huan Lu , De-shen Wang , Zhao-lei Zeng , Feng Wang , Feng-Hua Wang , Yu-Hong Li , Huai-Qiang Ju , Rui-Hua Xu

Rationale: The antitumor activity of high-dose ascorbate has been re-evaluated recently, but the mechanism underlying cell-specific sensitivity to ascorbate has not yet been clarified.

中文翻译:

药理学抗坏血酸抑制胃癌细胞生长与GLUT1过表达,并通过氧化还原调节增强奥沙利铂的功效。

理由:高剂量抗坏血酸的抗肿瘤活性最近已重新评估,但尚未明确细胞对抗坏血酸敏感性的机制。
更新日期:2018-05-01
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