Background: As one of the most effective triggers with high tissue-penetrating capability and non-invasive feature, ultrasound shows great potential for controlling the drug release and enhancing the chemotherapeutic efficacy. In this study, we report, for the first time, construction of a phase-changeable drug-delivery nanosystem with programmable low-intensity focused ultrasound (LIFU) that could trigger drug-release and significantly enhance anticancer drug delivery.

中文翻译：

---

低强度聚焦超声触发相变纳米液滴释放药物

背景：超声作为具有高组织穿透能力和非侵入性特征的最有效的触发器之一，在控制药物释放和增强化疗功效方面显示出巨大的潜力。在这项研究中，我们首次报告了具有可编程低强度聚焦超声（LIFU）的相变药物输送纳米系统的构建，该系统可以触发药物释放并显着增强抗癌药物的输送。