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Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2013–2014
Mass Spectrometry Reviews ( IF 6.6 ) Pub Date : 2018-04-17 , DOI: 10.1002/mas.21530
David J. Harvey 1
Affiliation  

This review is the eighth update of the original article published in 1999 on the application of Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2014. Topics covered in the first part of the review include general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, and arrays. The second part of the review is devoted to applications to various structural types such as oligo‐ and poly‐ saccharides, glycoproteins, glycolipids, glycosides, and biopharmaceuticals. Much of this material is presented in tabular form. The third part of the review covers medical and industrial applications of the technique, studies of enzyme reactions, and applications to chemical synthesis. © 2018 Wiley Periodicals, Inc. Mass Spec Rev 37:353–491, 2018.

中文翻译:

通过基质辅助激光解吸/电离质谱分析碳水化合物和糖缀合物:2013–2014年的更新

这篇综述是1999年发表的原始文章的第八次更新,该文章是关于基质辅助激光解吸/电离质谱(MALDI)质谱在碳水化合物和糖缀合物分析中的应用,并将该文献的覆盖范围延至2014年底。审查的第一部分中涵盖的主题包括一般方面,例如MALDI过程的理论,矩阵,衍生化,MALDI成像,片段化和阵列。综述的第二部分专门针对各种结构类型的应用,例如寡糖和多糖,糖蛋白,糖脂,糖苷和生物制药。这些材料大部分以表格形式呈现。审查的第三部分涵盖了该技术的医学和工业应用,酶反应的研究,及其在化学合成中的应用。©2018 Wiley Periodicals,Inc.质谱修订版37:353–491,2018年。
更新日期:2018-04-17
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