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Microglia-targeted candidates push the Alzheimer drug envelope
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2018-04-27 , DOI: 10.1038/nrd.2018.65
Asher Mullard

Microglia-targeted candidates push the Alzheimer drug envelope

Microglia-targeted candidates push the Alzheimer drug envelope, Published online: 27 April 2018; doi:10.1038/nrd.2018.65

Denali Therapeutics is taking a swing at neuroinflammation with a first-in-man trial of a RIPK1 inhibitor, while the company and others search for ways to target microglial biology more precisely.


中文翻译:

针对小胶质细胞的候选人推动了阿尔茨海默氏症的治疗

针对小胶质细胞的候选人推动了阿尔茨海默氏症的治疗

以小胶质细胞为目标的候选人推动了阿尔茨海默氏症的药物开发,在线发布:2018年4月27日; doi:10.1038 / nrd.2018.65

Denali Therapeutics通过RIPK1抑制剂的首次人体试验在神经发炎方面大放异彩,而该公司和其他公司正在寻找更精确地靶向小胶质细胞生物学的方法。
更新日期:2018-04-27
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