Peptides have been regarded as useful biomolecule templates to control the synthesis of various inorganic nanomaterials in mild conditions. Inspired by this, the easily self-assembled amyloid β (Aβ) peptide was developed as an alternative template to prepare Au nanostructures for the enhanced catalytic activity, for instance, the reduction of 4-nitrophenol. The presence of Aβ peptide assemblies with different structures could direct the nucleation of Au to form different Au nanostructures. Using the Aβ_25–35 monomers, nanoribbons, and nanofibrils prepared by the self-assembly in phosphate buffered (PB) solution at 0, 3, and 12 h, respectively, as templates could controllably prepare Au nanospheres, nanoribbons, and nanofibers, while the Aβ_25–35 monomers prepared by the self-assembly in water at 0 h could direct the synthesis of Au nanoflowers. The Aβ_25–35-templated Au nanostructures had different catalytic activities due to the size and structure effects, which however are significantly enhanced as compared with the template-free Au nanoparticles.

中文翻译：

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以生物启发性的方式合成具有增强催化活性的淀粉状蛋白β肽装配模板化的金纳米结构

肽已被认为是在温和条件下控制各种无机纳米材料合成的有用生物分子模板。受此启发，开发了易于自组装的淀粉样蛋白β（Aβ）肽作为替代模板，以制备Au纳米结构以增强催化活性，例如还原4-硝基苯酚。具有不同结构的Aβ肽组装体的存在可以指导Au的成核以形成不同的Au纳米结构。使用分别在磷酸盐缓冲（PB）溶液中自组装分别在0、3和12 h制备的_Aβ25-35单体，纳米带和纳米纤维，作为模板可以可控制地制备Au纳米球，纳米带和纳米纤维，而在Aβ _25-35通过在0 h水中自组装制备的单体可以指导Au纳米花的合成。所述Aβ _25-35 -templated的Au纳米结构由于尺寸和结构的影响，然而这是显著加强与无模板的Au纳米颗粒相比，有不同的催化活性。